Pfizer's Celebrex shown to be as safe as ibuprofen or naproxen: study
NEW ORLEANS (Reuters) - Pfizer Inc's Celebrex arthritis drug was shown to be at least as safe as the widely used prescription-strength versions of painkillers ibuprofen and naproxen, and does not appear to cause heart problems that spurred the withdrawal of rival Vioxx, according to a large 10-year study presented on Sunday.
Publication date: Available online 14 August 2018Source: Autoimmunity ReviewsAuthor(s): Kassem Sharif, Abdulla Watad, Louis Coplan, Benjamin Lichtbroun, Alec Krosser, Michael Lichtbroun, Nicola Luigi Bragazzi, Howard Amital, Arnon Afek, Yehuda ShoenfeldAbstractStress is defined as the pscyophysiological reaction in which the steady state is disturbed or threatened. Stress is not always perceived as a negative response. Stress results when environmental demands exceed an individuals' adaptive capacities. Autoimmune diseases are heterogeneous group of chronic diseases which occur secondary to loss of self antigen tolerance. ...
Authors: Okuda Y, Yamada T, Ueda M, Ando Y Abstract Objective To clarify the underlying diseases, clinical manifestations, and treatment strategies for AA amyloidosis (AAA) in Japanese patients. Methods We conducted a survey on Japanese patients with AAA treated between January 1, 2012, and December 31, 2014. Results A total of 199 patients with AAA were included in the present study. The underlying diseases of AAA were rheumatoid arthritis (60.3%), uncharacterized inflammatory disorders (11.1%), neoplasms (7.0%), other rheumatic diseases (6.5%), inflammatory bowel diseases (4.5%), chronic infection (4.5%), Castlem...
The data, published in the journal Rheumatology on Tuesday, suggested a 40 per cent greater chance of affected children developing RA as adults - even if they never grow-up to become smokers.
This report details new and worsening subcutaneous nodulosis in a case series of patients with rheumatoid arthritis treated with the monoclonal antibody tocilizumab.Journal of Medical Case Reports
Authors: Hernandez Bel L, Hernández Garfella ML, Chiarri Toumit C, Valenzuela Oñate C PMID: 30100239 [PubMed - as supplied by publisher]
Patients with rheumatoid arthritis who have had cancer can, in general, be treated with tumor necrosis factor inhibitors without increasing cancer recurrence risk, new data showed.Medscape Medical News
Jinjun Shan, Linxiu Peng, Wenjuan Qian, Tong Xie, An Kang, Bei Gao, Liuqing Di
Mikhaila Peterson, 26, of Toronto, says eating only beef has helped clear up her severe arthritis and depression. But Harley Street nutritionist Rhiannon Lambert has warned people to be wary.
RHEUMATOID arthritis is a type of joint pain condition that affects about 400,000 people in the UK. What is the condition, and what are the signs to look out for? This Morning ’s Dr Chris reveals the symptoms of the autoimmune condition.
ConclusionsIn this study, the chloroform soluble fraction of ‘KSL’ (seeds of C. minax) was found to exert an anti-RA activity significantly in vivo for the first time, which indicted this fraction might be used as a powerful therapeutic agent for arthritis treatments. Cassane diterpenes, as the main constituents in this fraction, showed the anti-inflammation activity through the regulation of cytokine expression, which might be developed as target-agents for this national herb further developing.Graphical abstract