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Pfizer's Celebrex shown to be as safe as ibuprofen or naproxen: study

NEW ORLEANS (Reuters) - Pfizer Inc's Celebrex arthritis drug was shown to be at least as safe as the widely used prescription-strength versions of painkillers ibuprofen and naproxen, and does not appear to cause heart problems that spurred the withdrawal of rival Vioxx, according to a large 10-year study presented on Sunday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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Authors: Carrera CG, Dapavo P, Malagoli P, Naldi L, Arancio L, Gaiani F, Egan CG, Di Mercurio M, Cattaneo A Abstract BACKGROUND: Few studies have compared the use of different biologics in a real-life setting in plaque psoriasis patients. OBJECTIVE: To compare the efficacy of biologics in psoriasis/psoriatic arthritis patients. METHODS: Patients treated with adalimumab, etanercept and ustekinumab for at least 16 weeks were included. Achievement of PASI90/100 response and time taken to achieve PASI90/100 response were measured. Logistic regression was used to evaluate the effect of psoriasis localization on ...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
ConclusionPrevalence of signs of abductor digiti quinti denervation on MRI was high in the studied population, suggesting that rheumatoid arthritis may be associated with inferior calcaneal nerve compression.
Source: Skeletal Radiology - Category: Radiology Source Type: research
ConclusionA majority of women with rheumatic diseases have successful pregnancies and deliver healthy babies, with the close and appropriate rheumatological, obstetric and neonatal monitoring.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Publication date: Available online 23 October 2017 Source:Regulatory Toxicology and Pharmacology Author(s): Zaher A. Radi, W. Mark Vogel, Phillip M. Bartholomew, Petra Koza-Taylor, Alexandros Papanikolaou, Todd Wisialowski, Prashant Nambiar, Douglas J. Ball Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis. In the 2-year carcinogenicity study with tofacitinib, increased incidence of hibernoma (a neoplasm of brown adipose tissue [BAT]) was noted in female rats at ≥30 mg/kg/day (≥41x human exposure multiples). Thus, signaling pathways within BAT were investigated by measuring BAT: wei...
Source: Regulatory Toxicology and Pharmacology - Category: Toxicology Source Type: research
Conclusion: Very limited evidence to support recreational activity and walking intervention was found for knee osteoarthritis, in the short-term on pain and physical function, respectively.
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Original Research Articles Source Type: research
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: REVIEW ARTICLE Source Type: research
ARTHRITIS symptoms include joint swelling and inflammation. This £1 fruit could help to reduce some of the condition’s painful effects.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Condition:   Rheumatoid Arthritis Interventions:   Other: Patient Educational Intervention;   Other: Patient Control Sponsors:   University of Alabama at Birmingham;   Pfizer Independent Grants for Learning and Change Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A new study of 50,000 people finds that those with rheumatoid arthritis had a 47 percent higher risk of COPD hospitalization than the general population.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Arthritis / Rheumatology Source Type: news
Condition:   Rheumatoid Arthritis Interventions:   Other: Patient Educational Intervention;   Other: Patient Control Sponsors:   University of Alabama at Birmingham;   Pfizer Independent Grants for Learning and Change Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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