Can mayonnaise cure my infertility?

A controversial treatment that has divided medical professionals is offering hope to women who have suffered multiple miscarriagesIt is a warm spring day, and I am sitting in a private clinic in Surrey with a drip in my arm. I am having an infusion of intralipids, a white emulsion of soybean oil and egg: mayonnaise, basically. On top of that, I am taking a daily dose of steroids. I have signed a form declaring that I am aware intralipids are not licensed for use in pregnancy, and that there is a lack of scientific evidence for their use in my condition; and I know that the steroids have potential side-effects ranging from psychosis to liver failure. Yet here I am, watching the mayonnaise make its way into my bloodstream, hoping this unproven treatment will protect the tiny twins I am carrying.After years of infertility and a miscarriage, I have decided to put my faith in reproductive immunology, a field of medicine that is either fantastically promising or utterly bogus, depending on whom you ask. Its critics see the treatments as bad medicine, and a cash cow for private fertility clinics. Its advocates, including women who finally have a healthy baby after four or five losses, think it could revolutionise the way we think about pregnancy. As for me, I feel I have nothing to lose. At the NHS hospital where I miscarried at the beginning of this year, I was told there was nothing I could do but go away and try again.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Fertility problems Family Health Society Life and style Source Type: news

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This study investigated the quality and quantity of eggs and embryos as well as the clinical pregnancy outcome in young infertile women with diminished ovarian reserve (DOR) after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). MATERIAL AND METHODS We retrospectively reviewed records of 4285 infertile women and divided them into 3 groups according to age and ovarian reserve: young women with normal ovarian reserve (n=1695), young women with DOR (n=1121), and older women with DOR (n=1469). RESULTS In young women with DOR, the proportion of high-quality embryos was significantly higher than in older women...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
ConclusionHysteroscopic surgery using cold graspers combined with electric loop by the HEOS is feasible and effective for treatment of DUL as it preserves the uterus and yields favorable reproductive outcomes. The cold surgery and fenestration method minimize electrical and thermal damage to the endometrium surrounding the myoma, consequently reducing surgical risks.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
CONCLUSIONS: Given its potential to reduce the miscarriage rate, LT4 supplementation is recommended for infertile women with SCH and/or TAI who are undergoing IVF/ICSI. However, additional population-based RCTs are needed to confirm this recommendation. PMID: 30249251 [PubMed - in process]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
ni ME Abstract Context: There is increasing evidence for MIS/AMH physiologic activity in the human uterus, so it is relevant to study how MIS/AMH levels impact pregnancy. Objective: To investigate the association of MIS/AMH levels with risk of adverse obstetric outcomes. Design: Retrospective cohort study. Setting: Academic fertility center. Patients: Women who became pregnant through in vitro fertilization (IVF) between January 2012-October 2016. Exclusion criteria were: oocyte donation, gestational carrier, multiple gestation, miscarriage before 20 weeks, medically indicated preterm deliverie...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Increased serum C-reactive protein (CRP) levels have recently been reported to reduce fecundity in healthy eumenorrheic women with a history of 1-2 pregnancy losses. 1 As subclinical systemic inflammation may impede maternal immune tolerance, implantation and embryonic development might be compromised. Inflammation could, thus, also serve as a causative factor for the substantial proportion of miscarriages that reveal normal karyotypes after analysis of products of conception (POCs). To evaluate in infertile women the relationship between pre-pregnancy CRP levels and POC karyotype was the objective of this study.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
Ovulation Induction with IUI is a common first step in the treatment of infertility given its lower cost and ease of implementation compared to IVF. Disadvantages include lower pregnancy rates and thus longer time to conception. PGT-A provides the advantage of lower miscarriage rates (SAB). We sought to compare the pregnancy outcomes and cost per cycle of IUI and IVF/ PGT-A.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
Abstract OBJECTIVE: To ascertain whether stress biomarker and psychological indices of stress may predict both conception and miscarriage rates in women undergoing in-vitro fertilization/ intracytoplasmic sperm injection (IVF/ ICSI). DESIGN: Prospective observational study. SETTING: A university-affiliated tertiary hospital. POPULATION OR SAMPLE: Infertility women who were undergoing fresh or frozen IVF/ICSI cycles. METHODS: Subjects were recruited to (1) completed validated psychological questionnaires (visual analogue scale of stress, state trait anxiety inventory, perceived stress scale, fer...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: BJOG Source Type: research
Abstract BACKGROUND: Pregnancies following assisted reproductive technology (ART) may have elevated potential risk of pregnancy loss (PL) when compared to natural conception. However, rare studies comprehensively analyzed the IVF/ICSI cycle-dependent factors for loss of clinical pregnancy. Therefore, we aimed to determine the ART subgroup-specific risks of PL throughout pregnancy and explore different risk factors for early miscarriage and late miscarriage among pregnancies conceived through ART. METHODS: A retrospective cohort study was launched in two infertility treatment centers in Nanjing and Changzhou i...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
AbstractAsherman ’s Syndrome (AS) is an acquired condition defined by the presence of intrauterine adhesions (IUA) that cause symptoms such as menstrual abnormalities, pelvic pain, infertility, recurrent miscarriage, abnormal placentation and attendant psychological distress. Classically, AS is considered an iatro genic disease triggered by trauma to the pregnant uterus. Different factors can cause the destruction of the endometrium, thus affecting the endometrial stem cell niche and creating IUAs. Curettage of the pregnant uterus appears to be the most common source of this destruction. Nevertheless, some AS cases h...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
Celiac disease (CD) is a disorder characterized by an autoimmune reaction triggered by sensitivity to gluten, the protein component of wheat, barley, and rye. Celiac disease is present in approximately 1% –2% of the general population, and existing studies have postulated a potential effect on duration of reproductive years, fertility, and pregnancy outcomes. There have been multiple meta-analyses of cohort studies and case–control studies that attempt to elucidate the association between reprodu ctive disorders and incidence of CD (1, 2); these studies found associations between unexplained infertility, recurr...
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
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