Treat-to-Target the New Goal in Lupus

(MedPage Today) -- An international task force has taken the first steps toward formulating a "treat to target" approach for the treatment of systemic lupus erythematosus (SLE), focusing on remission, damage prevention, and quality of life.
Source: MedPage Today Primary Care - Category: Primary Care Source Type: news

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ConclusionsLupus activity is not uncommon after starting hemodialysis but giving a prolonged immunosuppressive therapies is not necessary in all cases and should be given cautiously to avoid their side effects.
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
We report a 22-year-old female patient who presented at Cipto Mangunkusumo Teaching Hospital in Indonesia, with profuse and prolonged vaginal bleeding without any other accompanying symptoms. She had a history of polyarthralgias, fever, bleeding gums, anemia, and thrombocytopenia 3 months earlier. Abdominal ultrasound examination revealed bilateral hydronephrosis and a thickened bladder wall; the other organs were normal. Laboratory examination confirmed the diagnosis of SLE complicated by lupus nephritis and lupus cystitis. The patient responded well to the treatment with methylprednisolone. The vaginal bleeding stopped w...
Source: Case Reports in Nephrology and Dialysis - Category: Urology & Nephrology Source Type: research
Arthritis&Rheumatology,Volume 0, Issue ja, -Not available-.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Source Type: research
Arthritis&Rheumatology,Volume 0, Issue ja, -Not available-.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Source Type: research
Authors: Peschken CA, Wang Y, Abrahamowicz M, Pope J, Silverman E, Sayani A, Iczkovitz S, Ross J, Zummer M, Tucker L, Pineau C, Levy D, Hudson M, Hitchon CA, Huber AM, Smith CD, Avina-Zubieta A, Arbillaga H, Chédeville G, Wynant W, Fortin PR, CaNIOS 1000 Faces Investigators Abstract OBJECTIVE: Persistent systemic lupus erythematosus (SLE) disease activity is associated with increased morbidity and mortality. In a multicenter cohort of patients with prevalent SLE, we described persistence, patterns, and predictors of change in disease activity over time. METHODS: Based on SLE Disease Activity Index (SLEDA...
Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research
Conditions:   Lupus Nephritis;   Lupus Erythematosus Interventions:   Drug: Mesenchymal stromal cells (MSC);   Drug: Placebo Sponsors:   Red de Terapia Celular;   Hospital del Río Hortega;   Hospital Clínico Universitario de Valladolid;   University of Valladolid Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
(University of Edinburgh) New discoveries about the most common form of the autoimmune disease lupus could improve diagnosis and treatment of the condition in black Africans.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Journal of the European Academy of Dermatology and Venereology,Volume 0, Issue ja, -Not available-.
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Source Type: research
We present a 43-year-old African American male that presented to the dermatology clinic with an 18-month history of non-pruritic, violaceous, scaling patches and plaques most prominent on the malar cheeks, upper chest and upper back. He had been evaluated at an outside hospital with a high suspicion for cutaneous lupus erythematosus (CLE) and seborrheic dermatitis. However, repeated biopsies revealed non-specific spongiotic dermatitis, not consistent with CLE or seborrheic dermatitis. Over the subsequent months, he received treatment for both conditions without improvement in his symptoms. When he was referred to our derma...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
In this study, 26 patients with LN and 26 healthy individuals were included. The plasma levels of the microRNAs were evaluated by a quantitative real-time PCR. Moreover, the correlation of circulating plasma microRNAs with disease activity and pathological findings along with their ability to distinguish patients with LN were assessed. Results: Plasma levels of miR-125a (P = 0.048), miR-146a (P = 0.005), and miR-155 (P
Source: BioImpacts - Category: Research Tags: Bioimpacts Source Type: research
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