Nigeria: Studies Show Tomatoes Can Beat Skin Cancer, Male Infertility, Others

[Guardian] Can eating lots tomatoes provide the elusive cure for wrinkles, skin and prostate cancer, hypertension and male infertility?
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Authors: Frost ML, Hrynewycz K, Hanke CW Abstract Tumor thickness has been a key tool for prognosis of melanoma. However, with the advent of gene expression profile (GEP) assays for melanoma and the discovery of multiple melanoma subtypes, it is time to reassess how we view tumor thickness as a prognostic indicator.Herein we present ten questions for consideration by the shrewd practitioner when considering prognostic factors of melanoma. J Drugs Dermatol. 2019;18(2):148-151. PMID: 30794365 [PubMed - as supplied by publisher]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Conclusion: The histologic findings of BCCs treated with vismodegib correlate with clinical response. J Drugs Dermatol. 2019;18(2):136-138. PMID: 30794363 [PubMed - as supplied by publisher]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Conclusions: Superficial radiation therapy is an effective option for eliminating BCC and SCC on lower extremities of patients who opt for nonsurgical treatment. Using SRT for BCC and SCC in elderly patients resulted in a 97.4% cure rate. J Drugs Dermatol. 2019;18(2):130-134. PMID: 30794362 [PubMed - as supplied by publisher]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Publication date: April 2019Source: Redox Biology, Volume 22Author(s): Daniel S. de Jesus, Evan DeVallance, Yao Li, Micol Falabella, Danielle Guimaraes, Sruti Shiva, Brett A. Kaufman, Mark T. Gladwin, Patrick J. PaganoAbstractPulmonary arterial hypertension (PAH) is a complex degenerative disorder marked by aberrant vascular remodeling associated with hyperproliferation and migration of endothelial cells (ECs). Previous reports implicated bone morphogenetic protein antagonist Gremlin 1 in this process; however, little is known of the molecular mechanisms involved. The current study was designed to test whether redox signal...
Source: Redox Biology - Category: Biology Source Type: research
Publication date: Available online 23 February 2019Source: Advances in Biological RegulationAuthor(s): Alice Domenichini, Jeanne S. Edmands, Aleksandra Adamska, Romana-Rea Begicevic, Silvano Paternoster, Marco FalascaAbstractCancer stem cells are a population of slow-cycling cells within the tumour bulk, with self-renewal capacity that attract interest as a therapeutic target. In highly heterogeneous tumours, like pancreatic ductal adenocarcinoma (PDAC) however, the characterisation of cancer stem cells has led to controversial results due to the lack of consensus on specific markers. Here we investigated the characteristi...
Source: Advances in Biological Regulation - Category: Biology Source Type: research
Publication date: Available online 22 February 2019Source: Carbohydrate PolymersAuthor(s): Elham Gholibegloo, Tohid Mortezazadeh, Fatemeh Salehian, Ali Ramazani, Massoud Amanlou, Mehdi KhoobiAbstractA novel β-cyclodextrin-based nanosponge (CDNS) was proposed as curcumin (CUR) delivery system improving pharmacokinetics and anticancer activity of CUR. The effect of molar ratio of Epiclon (EPI) as cross-linker and β-cyclodextrin (βCD) on the porosity, surface area, swelling ratio, CUR solubility and loading capacity, rate of drug release and selective toxicity of the CDNSs was fully investigated. The high degre...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: May 2019Source: Biomedical Signal Processing and Control, Volume 51Author(s): Sameena Pathan, K. Gopalakrishna Prabhu, P.C. SiddalingaswamyAbstractA clinically oriented Computer-Aided Diagnostic (CAD) system is of prime importance for the diagnosis of melanoma, since the deadly disease is associated with high morbidity and mortality. Unfortunately, the development of CAD tools is hampered by several issues, such as (i) smooth boundaries between the lesion and the surrounding skin, (ii) subtlety of features between the melanoma and non-melanoma skin lesions, and (iii) lack of reproducibility of CAD systems...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
Publication date: Available online 22 February 2019Source: Biochimica et Biophysica Acta (BBA) - General SubjectsAuthor(s): Mojtaba Falahati, Farnoosh Attar, Majid Sharifi, Thomas Haertlé, Jean-François Berret, Rizwan Hasan Khan, Ali Akbar SabouryAbstractNanoparticle (NP)–protein complexes exhibit the “correct identity” of NP in biological media. Therefore, protein–NP interactions should be closely explored to understand and to modulate the nature of NPs in medical implementations. This review focuses mainly on the physicochemical parameters such as dimension, surface chemistry, the mo...
Source: Biochimica et Biophysica Acta (BBA) General Subjects - Category: Biochemistry Source Type: research
Publication date: 15 May 2019Source: Sensors and Actuators B: Chemical, Volume 287Author(s): Yongfei Huang, Yongbin Zhang, Fangjun Huo, Jianbin Chao, Caixia YinAbstractThe reactive oxygen species (ROS) including hypochlorous acid (HOCl), on the one hand they can regulate physiological function in our living organisms, on the other hand abnormal concentration of ROS would induce a series of biomacromolecules damage and further endanger virtually all aspects of human health. Especially it can be directly related to cancer. Thus to elucidate and visualize their concentration is very imminent. Before many fluorescent probes we...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
CONCLUSIONS: Male infertility is a proxy of the overall male health status. Physicians should comprehensively assessed men presenting for couple infertility and properly followed-up these patients given their higher risk of developing cancer. PMID: 29595040 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
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