Outpatient Medication Use in Chinese Geriatric Patients Admitted for Falls: A Case–Control Study at an Acute Hospital in Hong Kong

The study objective was to investigate the association of polypharmacy and medications with patient falls resulting in hip fractures among community-living geriatric patients. A case–control study was conducted at an acute public hospital in Hong Kong. The study population was community-living Chinese patients aged 65 years and above who were admitted for falls resulting in hip fractures during an 18-month study period. Each of these patients was matched to a control patient with the same age and sex, but without falls and fractures. Data were collected from electronic patient record. Data of 170 cases and 170 controls were eventually collected. The following variables associated with increased risk of falls resulting in hip fractures remained statistically significant after multivariate logistic regression, including benign prostatic hyperplasia [odds ratio (OR) = 2.654; 95% confidence interval (CI), 1.105–6.378; P = 0.029], first-generation antihistamines (OR = 3.176; 95% CI, 1.044–9.664; P = 0.042), antiparkinson medications (OR = 3.754; 95% CI, 1.158–12.169; P = 0.027), osteoporosis (OR = 3.159; 95% CI, 1.167–8.552; P = 0.024), and use of walking aids (OR = 2.543; 95% CI, 1.544–4.188; P
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Original Articles Source Type: research