PR1 Peptide Vaccine May Aid Leukemia Remission PR1 Peptide Vaccine May Aid Leukemia Remission

PR1 peptide vaccine may benefit many patients with myeloid leukemia, chronic myeloid leukemia and myelodysplastic syndrome, findings from an early clinical trial suggest.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Public Health & Prevention News Source Type: news

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Authors: Corella Aznar EG, Ayerza Casas A, Carboné Bañeres A, Calvo Escribano MÁC, Labarta Aizpún JI, Samper Villagrasa P Abstract BACKGROUND: Survival of childhood acute lymphoblastic leukaemia involves an increasing risk of long-term morbidities. Due to the impact of cancer treatment and comorbidities, AL survivors may experience a decrease in their health-related quality of life. OBJECTIVE: We aimed to describe the long-term comorbidities, related quality of life and their development predictors in these survivors. METHODS: cross-sectional study of 54 survivors aged ≥18 and...
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Authors: Aleem S Abstract BACKGROUND: Diabetes Mellitus (DM) is an advanced and chronic endocrine disorder characterized by an insufficiency of insulin secretion from pancreatic β-cells and liver, adipose tissues, and skeletal muscles. OBJECTIVE: The main objective of this study is to understand the mechanism and genes which are responsible for the prevalence of diabetes. The study also covers various types of diabetic complications with special reference to insulin role and defects. METHODS: The scientific literature and patents were reviewed and analyzed based on their suitability and relevance to th...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research
We report the case of a 66-year old gentleman who was transferred to our facility with acute abdominal pain. A computed tomography (CT) scan was obtained after pre-medication because of contrast dye allergy. His past medical history included a cardiac transplant and congestive heart failure (ejection fraction 20%).
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Abstracts Presented to the Southern California Vascular Surgery Society Source Type: research
Publication date: Available online 19 July 2018Source: Academic PediatricsAuthor(s): Alison Saville, Peter Szilagyi, Laura Helmkamp, Christina Albertin, Dennis Gurfinkel, Sitaram Vangela, L. Miriam Dickinson, Xinkai Zhou, Heather Roth, Allison KempeAbstractObjectivesChildhood influenza vaccination rates remain sub-optimal. Provider perceptions on strategies to achieve universal vaccination are needed. We assessed perceptions and attitudes of primary care providers across two states regarding two strategies to potentially bolster rates: Centralized-Reminder/Recall (C-R/R), such as R/R from state immunization registries; and...
Source: Academic Pediatrics - Category: Pediatrics Source Type: research
Publication date: Available online 19 July 2018Source: Leukemia Research ReportsAuthor(s): Grace Xiuqing Li, Lan Wang, Bassam Yaghmour, Giridharan Ramsingh, George YaghmourAbstractActivating mutations in FLT3 in acute myeloid leukemia (AML) portend a poor prognosis, and targeting FLT3 with a tyrosine kinase inhibitor has been an area of intense research recently. Most FLT3 mutated AML patients undergo hematopoietic stem cell transplantation (HSCT) as standard of care but a significant proportion of patients relapse. Although the use of FLT3 inhibitors in the pre-HSCT perspective is more clearly defined, its use in the post...
Source: Leukemia Research Reports - Category: Hematology Source Type: research
The objective of this study is to analyze the relationship between chronic rhino-sinusitis (CRS) and systemic symptoms in patients with IgG4-related disease (IgG4-RD).Patients and methodsThe patients with IgG4-RD, confirmed by restrict association with clinical and histopathological manifestations between March 2013 and July 2016, were enrolled and followed-up for 1  year at the Tongren Hospital, Capital Medical University. The patients were divided into two groups: the case group included IgG4-RD patients with CRS confirmed by clinical and imaging, while the control group included IgG4-RD patients without CRS confirm...
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
ConclusionThis study showed a significant association between polypoid change of anterior free border of middle turbinate and nasal polyp relapse. This new and simple criterion of severity of CRSwNP could have clinical implications.
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
Publication date: July 2018Source: The Journal of Prosthetic Dentistry, Volume 120, Issue 1Author(s): Ippei Hamanaka, Kota Isshi, Yutaka TakahashiAbstractThis clinical report describes the management of a patient who had a metal allergy and had difficulty sitting in a dental chair for an extended period. The presented treatment used an intraoral scanner and computer-aided design and computer-aided manufacturing (CAD-CAM) to fabricate a nonmetal clasp denture. The described procedure may reduce patient discomfort and chair-time.
Source: The Journal of Prosthetic Dentistry - Category: Dentistry Source Type: research
ConclusionCarriage of AAI devices is suboptimal in young adolescents prescribed AAIs, particularly when young adolescents are independent of parental supervision.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Authors: Garg AD, Elsen S, Krysko DV, Vandenabeele P, de Witte P, Agostinis P Abstract [This corrects the article DOI: 10.18632/oncotarget.4754.]. PMID: 30018752 [PubMed - in process]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
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