Eszopiclone-induced Parasomnia with Suicide Attempt: A Case Report
Conclusion
The possibility for adverse effects, including life-threatening events, when taking eszopiclone should be considered by all prescribers. The pharmacological profile of eszopiclone suggests a potential for a greater risk of adverse events than with other benzodiazepine-like hypnotics such as zolpidem, which has a one-percent risk for sleep-related amnestic behaviors.[10] This risk increases further with concomitant administration of monoaminergic drugs like SSRIs. The risk for these behaviors among patients taking eszopiclone is yet to be quantified and presents an opportunity for future research endeavors. Regardless, other evidence-based treatments for insomnia (e.g., cognitive behavioral therapy, biofeedback, sedating antidepressants) should always be considered prior to sedative-hypnotic administration, and caution should be exercised when prescribing these medications.
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Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: ICN Online Editor Tags: Case Report Current Issue Depression Mood Disorders Psychiatry Psychopharmacology Sleep Disorders benzodiazepine-like drug reaction Eszopiclone hypnotic insomnia parasomnia sedative Source Type: research
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