Collective cell migration of thyroid carcinoma cells: a beneficial ability to override unfavourable substrates

ConclusionsOur data indicate that collective migration enables tumor cells to cross otherwise unfavourable substrate areas. This capacity seems to be independent of intercellular communication via gap junctions, whereas Rac1-dependent intracellular signalling seems to be essential.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research