Dynamic Modulation of Microglia/Macrophage Polarization by miR-124 after Focal Cerebral Ischemia

This study indicates that miR-124 administration before the peak of the pro-inflammatory process of stroke is most effectiv e in support of increasing the rehabilitation opportunity in the sub-acute phases of stroke. Our findings highlight the important role of immune cells after stroke and the therapeutic relevance of their polarization balance.
Source: Journal of NeuroImmune Pharmacology - Category: Drugs & Pharmacology Source Type: research