Aneuploidy of a murine immortalized endothelial cell line, MS1

Conclusion MS1 cells are aneuploid and activate H2AX to a greater extent than NECs do. MS1 cells resemble TECs in terms of the proliferative phenotype and aneuploidy. Thus, MS1 may be a good cell line for studies on the relation between chromosomal instability and a DDR in nonmalignant cells.
Source: Journal of Oral Biosciences - Category: Biomedical Science Source Type: research