Interleukin-23 Secreted by Activated Macrophages Drives {gamma}{delta}T Cell Production of Interleukin-17 to Aggravate Secondary Inȷury After Intracerebral Hemorrhage [Stroke]

ConclusionsTogether, our results reveal the importance of the IL‐23/IL‐17 inflammatory axis in secondary brain injury after ICH and thus provide a new therapeutic target for ICH treatment.

Source: JAHA:Journal of the American Heart Association - October 10, 2016 Category: Cardiology Authors: Zhong, Q., Zhou, K., Liang, Q.-L., Lin, S., Wang, Y.-C., Xiong, X.-Y., Meng, Z.-Y., Zhao, T., Zhu, W.-Y., Yang, Y.-R., Liao, M.-F., Gong, Q.-W., Liu, L., Xiong, A., Hao, J., Wang, J., Yang, Q.-W. Tags: Blood-Brain Barrier, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Research Source Type: research