Dengue-associated acute encephalitis syndrome cases in Son La Province, Vietnam in 2014.

The objectives of this paper were to determine the proportion of encephalitic patients due to JEV during the 2014 outbreak in Son La Province in Vietnam and to find the association of DENV in non-JEV viral encephalitis cases. Out of 90 patients, 6 (6.7%) were positive for anti-JEV IgM, 5 (5.6%) were positive for anti-DENV IgM, 30 (33.3%) were positive for both anti-JEV and anti-DENV IgM and 56 (62.2%) were positive for flavi IgG. Five AES patients positive with anti-DENV IgM in at least one of paired serum samples were confirmed to have DENV by neutralization tests. The incidence of JEV infection rate was high. There is still a need for Japanese encephalitis national immunization program. The noticeable occurrence of dengue was not reported in Son La province between 2013-2014. Our data suggested that in addition to JEV, DENV was also a causative agent of AES in 2014 in Son La province and this finding also confirmed the local occurrence of dengue. PMID: 27795473 [PubMed - as supplied by publisher]
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research