Hybrid polymeric matrices for oral modified release of Desvenlafaxine succinate tablets

Conclusion: A controllable release pattern of DSV was achieved using Methocel, Maltodextrin and SCMC. The obtained results could be used as a platform to control the release of cationic water soluble drugs that suffer from side effects associated with their initial burst after oral administration.
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research