Strong antineoplastic effects of metformin in preclinical models of liver carcinogenesis

Conclusions The potent antitumoral effects of metformin in multiple preclinical models implicating several molecular mechanisms provide strong rationale for clinical trials including combination studies in hepatocellular carcinoma patients.

Source: Clinical Science - October 31, 2016 Category: Biomedical Science Authors: Cauchy, F., Mebarki, M., Leporq, B., Laouirem, S., Albuquerque, M., Lambert, S., Bourgoin, P., Soubrane, O., van Beers, B., Faivre, S., Bedossa, P., Paradis, V. Tags: PublishAheadOfPrint Source Type: research