Gene Methylation Profiling in Sinonasal Adenocarcinoma and Squamous Cell Carcinoma

Conclusion ITAC carries a higher number and a different profile of gene methylations as compared with SNSCC. Gene methylation plays a greater role in papillary and colonic ITAC subtypes, which may indicate a different tumorigenic pathway for these ITAC subtypes. These findings could be used as prognosticators and may have implications for future individualized therapies based on epigenetic changes.
Source: Otolaryngology - Head and Neck Surgery - Category: ENT & OMF Authors: Tags: Head and Neck Surgery Source Type: research