Gene Methylation Profiling in Sinonasal Adenocarcinoma and Squamous Cell Carcinoma
Conclusion
ITAC carries a higher number and a different profile of gene methylations as compared with SNSCC. Gene methylation plays a greater role in papillary and colonic ITAC subtypes, which may indicate a different tumorigenic pathway for these ITAC subtypes. These findings could be used as prognosticators and may have implications for future individualized therapies based on epigenetic changes.
Source: Otolaryngology - Head and Neck Surgery - Category: ENT & OMF Authors: Costales, M., Lopez-Hernandez, A., Garcia-Inclan, C., Vivanco, B., Lopez, F., Llorente, J. L., Hermsen, M. A. Tags: Head and Neck Surgery Source Type: research
More News: Academia | Adenocarcinoma | Cancer & Oncology | Carcinoma | ENT & OMF | Genetics | Mucinous Carcinoma | Skin Cancer | Squamous Cell Carcinoma | Study