New sperm research could lead to cut in infertility rate

Sperm and mathematics don ’t appear to be the likeliest of bedfellows, but new research bringing the two together could lead to devices that could cut infertility rates.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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Conclusion(s)The presence of lipid receptors/transporters and HSL in human spermatozoa suggests their role in the process of maturation/capacitation. The changes in the expression of lipid receptors/transporters and the lack of the 130-kDa HSL isoform in obese patients prevent the hydrolysis of cholesterol esters internalized by these receptors, and favor their accumulation in the cytoplasm of the spermatozoa that could contribute to lipotoxicity and infertility.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
AbstractEndometriosis is a benign chronic inflammatory disease that mostly affects women of reproductive age. The disease is often associated with dysmenorrhoea, pelvic and non-menstrual pain, and infertility. NSAIDs and hormonal suppression therapies (i.e. estroprogestins and progestins) are generally used as first-line treatment to alleviate pain symptoms. Second-line options include other hormonal suppressants, such as gonadotropin-releasing hormone agonists and antagonists and, less commonly, danazol and aromatase inhibitors.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research
Evaluation of the effects of antioxidant treatment on sperm parameters and pregnancy rates in infertile patients after varicocelectomy: a randomized controlled trial, Published online: 18 January 2019; doi:10.1038/s41443-018-0109-4Evaluation of the effects of antioxidant treatment on sperm parameters and pregnancy rates in infertile patients after varicocelectomy: a randomized controlled trial
Source: International Journal of Impotence Research - Category: Urology & Nephrology Authors: Source Type: research
AbstractPurposeThe aim of the present study was to examine the effects of planned yoga practices on stress levels in infertile women.Design and MethodsThis randomized controlled study included 128 volunteer women who were registered at a private in vitro fertilization (IVF) clinic and received infertility treatment. The patients in the experimental group took part in the yoga program twice a week for 6 weeks. A personal information form and The Copenhagen Multi ‐center Psychosocial Infertility (COMPI) Fertility Problem Stress Scale were used to collect data.FindingsThe differences between the mean scores of the control a...
Source: Perspectives in Psychiatric Care - Category: Psychiatry Authors: Tags: ORIGINAL ARTICLE Source Type: research
The objective of this study was to map the sites of localization of ion channels ENaC and CFTR along the length of the mouse and rat epididymis using confocal microscopic imaging. The integrity of the fine structure of the tissues was verified by fluorescent phalloidin staining of actin filaments visualized by high-resolution confocal microscopy. The 2D and 3D images showed preservation of the stereocilia. Based on these images we determined morphometric parameters of the epithelial cells and ducts. ENaC and CFTR immunofluorescence appeared almost continuously on the apical membrane of caput and in smooth muscle myoid cell...
Source: Journal of Molecular Histology - Category: Laboratory Medicine Source Type: research
By Ruchika Tulshyan, Contributor, The OptimistJanuary 17, 2019Fatimata Sy  talks to The Optimist about her work, the future of family planning, and her own audacious personal goal.When it launched in 2011, theOuagadougou Partnership set an audacious goal for 2020: Increase the number of women using modern contraceptives by at least 2.2 million in nine francophone West African countries.Historically, not many women in the region used contraceptives because of socio-cultural factors and infrastructure challenges. But members of the Partnership were determined to prove that with the right approach, family pla...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: Ouagadougou Partnership Coordination Unit Family Planning & Reproductive Health Source Type: news
Publication date: Available online 17 January 2019Source: Academic RadiologyAuthor(s): Juanfang Liu, Liping Han, Xinwei HanRationale and ObjectivesTo report the effect of pregnancy on patients who have undergone pelvic vein embolization with pelvic congestion syndrome, which was suspected to be the only cause of infertility.Material and MethodsData from a total of 12 women (mean age: 36.5 ± 4.3 years, range: 29–45 years) were collected between May 2013 and June 2016. Transvenous embolization with fibre platinum coils combined with anhydrous alcohol was performed in unilateral or bilateral ovarian veins after t...
Source: Academic Radiology - Category: Radiology Source Type: research
CONCLUSIONS: The results of the present proof of concept study suggest that NTAP could be a novel method to reduce and/or prevent the formation of peritoneal adhesions after abdominopelvic surgeries. PMID: 30644787 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
AbstractGenetic anomalies are known to affect about 15% of infertile patients with azoospermia or severe oligozoospermia. Despite a throughout diagnostic work-up, in up to the 72% of the male partners of infertile couples, no etiological factor can be found; hence, the cause of infertility remains unclear. Recently, several novel genetic causes of spermatogenic failure (SPGF) have been described. The aim of this review was to collect all the available evidence of SPGF genetics, matching data from in-vitro and animal models with those in human beings to provide a comprehensive and updated overview of the genes capable of af...
Source: Human Genetics - Category: Genetics & Stem Cells Source Type: research
ConclusionThere is a significant causal association between most diseases present at the starting time of the first intended oocyte retrieval cycle and lower odds of live birth in the first IVF/ICSI treatment.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
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