Valsartan Protects against Contrast-Induced Acute Kidney Injury in Rats by Inhibiting Endoplasmic Reticulum Stress-Induced Apoptosis.

In conclusion, valsartan could protect against meglumine diatrizoate-induced kidney injury in rats by inhibiting the ER stress-induced apoptosis, making it a promising strategy for preventing CI-AKI.
PMID: 27781957 [PubMed - as supplied by publisher]

Source: Current Vascular Pharmacology - October 24, 2016 Category: Drugs & Pharmacology Authors: Sun Y, Peng PA, Ma Y, Liu X, Yu Y, Jia S, Xu X, Wu S, Zhou Y Tags: Curr Vasc Pharmacol Source Type: research