Bone loss and aggravated autoimmune arthritis in HLA-DR β1-bearing humanized mice following oral challenge with Porphyromonas gingivalis

The linkage between periodontal disease and rheumatoid arthritis is well established. Commonalities among the two are that both are chronic inflammatory diseases characterized by bone loss, an association with...

Source: Arthritis Research and Therapy - October 26, 2016 Category: Rheumatology Authors: Indra Sandal, Anastasios Karydis, Jiwen Luo, Amanda Prislovsky, Karen B. Whittington, Edward F. Rosloniec, Chen Dong, Deborah V. Novack, Piotr Mydel, Song Guo Zheng, Marko Z. Radic and David D. Brand Source Type: research