Adrenal insufficiency in neonates after cardiac surgery with cardiopulmonary bypass

ConclusionsNeonatal cardiac surgery with CPB and preoperative methylprednisolone leads to AI as determined by low‐dose ACTH stimulation test in one‐third of patients. AI is associated with increased serum lactate and colloid resuscitation in OR. Impact of preoperative methylprednisolone on results is not defined. Benefit of postoperative steroid administration in neonates with post‐CPB AI warrants further investigation.

Source: Pediatric Anesthesia - October 24, 2016 Category: Anesthesiology Authors: Jack H. Crawford, Matthew S. Hull, Santiago Borasino, Brad L. Steenwyk, Kristal M. Hock, Kevin Wall, Jeffrey A. Alten Tags: Research Report Source Type: research