Advanced glycation endproducts trigger autophagy in cadiomyocyte Via RAGE/PI3K/AKT/mTOR pathway

Conclusion:
This study provides evidence that AGEs induces cardiomyocyte autophagy by, at least in part, inhibiting the PI3K/Akt/mTOR pathway via RAGE.

Source: Cardiovascular Diabetology - April 14, 2014 Category: Cardiology Authors: Xuwei HouZhaohui HuHanying XuJian XuShunrong ZhangYigang ZhongXiuying HeNingfu Wang Source Type: research