What's Old is New Again - A review of the current evidence of colchicine in cardiovascular medicine.

What's Old is New Again - A review of the current evidence of colchicine in cardiovascular medicine.
Curr Cardiol Rev. 2016 Oct 13;
Authors: Tan GM, Yan BP
Abstract
Colchicine is a well-established drug approved by the Food and Drug Administration (FDA) for the prevention and treatment of gout. It processes unique anti-inflammatory properties. Interests in the usage of colchicine in cardiovascular medicine have been rekindled recently with several large trials been carried out to investigate its efficacy in treatment of various cardiac conditions including pericarditis, postpericardiotomy syndrome, atrial fibrillation and coronary artery disease. In this review, the basic pharmacological properties of colchicine will be discussed, and the evidences of its benefits for different applications in cardiovascular medicine will be reviewed.
PMID: 27758695 [PubMed - as supplied by publisher]

Source: Current Cardiology Reviews - October 21, 2016 Category: Cardiology Tags: Curr Cardiol Rev Source Type: research