MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension

Conclusion
This study is the first to define a role for aberrant miR153 contributing to the hypertensive state through targeting of KCNQ4 in an animal model of hypertension, raising the possibility of the use of miR153-related therapies in vascular disease.

Source: Cardiovascular Research - October 20, 2016 Category: Cardiology Authors: Carr, G., Barrese, V., Stott, J. B., Povstyan, O. V., Jepps, T. A., Figueiredo, H. B., Zheng, D., Jamshidi, Y., Greenwood, I. A. Tags: Vascular biology Source Type: research