The nuclear pore protein Nup153 associates with chromatin and regulates cardiac gene expression in dystrophic mdx hearts

Conclusions
Our data indicate that Nup153 is an epigenetic regulator which, upon altered NO signalling, mediates the activation of genes potentially associated with early dystrophic cardiac remodelling.

Source: Cardiovascular Research - October 20, 2016 Category: Cardiology Authors: Nanni, S., Re, A., Ripoli, C., Gowran, A., Nigro, P., DAmario, D., Amodeo, A., Crea, F., Grassi, C., Pontecorvi, A., Farsetti, A., Colussi, C. Tags: Cardiac biology and remodelling Source Type: research