Comparative assessment of antibiotic potency loss with time and its impact on antibiotic resistance

AbstractA wide range of diverse antibiotics is available in the current world ’s drug market, which is mostly being used for the treatment of infectious diseases in humans as well as in veterinary. A large number of new antibiotics are continuously being added to the existing list. However, at the same time, most of the pathogens have tended to overcome antibiotic stress du e to their specific mutations and adaptations with time. Hence, several antibiotics turn to be non-effective in the long run. Moreover, antibiotics also lose their effectiveness with time as they approach their expiry period. The goal of this study is to compare and elucidate the changes in the pote ncy and effectiveness of antibiotic with time. The present study uses three different antibiotics known as ciprofloxacin, erythromycin, and tetracycline of fluoroquinolones, macrolides, and tetracyclines groups, respectively, which are collected in two forms, brand new and recently expired.Escherichia coli, gram-negative intestinal bacteria, andStaphylococcus aureus, gram-positive bacteria, have been used as test microorganisms. The obtained results show a significant loss in the potency and effectiveness of antibiotic as they progressively decompose with time. However, there is a huge possibility to recycle it as the present study suggests.
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research
More News: Pathology