DNA ligase IV syndrome; a review

DNA ligase IV deficiency is a rare primary immunodeficiency, LIG4 syndrome, often associated with other systemic features. DNA ligase IV is part of the non-homologous end joining mechanism, required to repair ...

Source: Orphanet Journal of Rare Diseases - October 7, 2016 Category: Internal Medicine Authors: Thomas Altmann and Andrew R. Gennery Source Type: research