The ABCs of Cerebral Palsy

Approximately 2 in 1,000 children are born with the neurological disorder.
Source: U.S. News - Health - Category: Consumer Health News Authors: Source Type: news

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Conclusion and implications This study demonstrates anticipatory action planning, measured using the sword task, does not improve with age in children with unilateral CP and is not related to bimanual performance or laterality. Future studies of anticipatory action planning in children with unilateral CP should consider using measures that require effective anticipatory action planning for successful task completion rather than end state comfort.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
AbstractOsteoporosis is a common complication of cerebral palsy and Rett ’s syndrome. It is responsible for multiple fractures, bone pain, and impaired quality of life. In case of Rett’s syndrome, a specific dysfunction of osteoblasts causes bone fragility. We observed the effects of annual zoledronic acid (ZA) infusion in a cohort of children with cerebral palsy and Rett’s syndrome. 27 children under 18 years (19 with cerebral palsy and 8 girls with Rett syndrome confirmed by MCEP2 mutation) were treated with an annual injection of 0.1 mg/kg (max 4 mg) of ZA. Calcium and vitamin D were com...
Source: Calcified Tissue International - Category: Orthopaedics Source Type: research
Conclusions and implicationsThe findings suggest that children with CP are at risk for reading and spelling delays when they have poor phonological processing, visual sequential memory and perception of visuospatial relationships. The implications of the findings for classroom practice are discussed.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
The objective was to report the five-year evolution in upper limb function and identify factors influencing time trends. Eighty-one children (mean age 9 y and 11 mo, SD 3 y and 3 mo) were assessed at baseline with follow-up after 6 months, 1, and 5 years. Passive range of motion (PROM), tone, muscle, and grip strength were assessed. Activity measurements included Melbourne Assessment, Jebsen-Taylor test, Assisting Hand Assessment (AHA), and ABILHAND-Kids. At 5-year follow-up, PROM (p
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
Dr. Michael Kruer has received the first federally funded grant to research genetic causes of a condition that affects 1 in 250 children.
Source: The University of Arizona: Health - Category: Universities & Medical Training Authors: Source Type: research
Atypical cerebral palsy: genomics analysis enables precision medicine, Published online: 13 December 2018; doi:10.1038/s41436-018-0376-yAtypical cerebral palsy: genomics analysis enables precision medicine
Source: Genetics in Medicine - Category: Genetics & Stem Cells Authors: Source Type: research
ConclusionFuture work in this domain should continue to leverage longitudinal evaluations of preterm infants which include both neuroimaging and detailed serial neurodevelopmental assessments to further characterize relationships between imaging measures and impairment, information necessary for advancing our understanding of modifiable risk factors underlying these disorders and best practices for improving neurodevelopmental trajectories in this high-risk clinical population.
Source: Journal of Neurodevelopmental Disorders - Category: Neurology Source Type: research
Abstract Cerebral palsy (CP) is predominantly a disorder of movement, with evidence of sensory-motor dysfunction. CIMT1 is a widely used treatment for hemiplegic CP. However, effects of CIMT on somatosensory processing remain unclear. To examine potential CIMT-induced changes in cortical tactile processing, we designed a prospective study, during which 10 children with hemiplegic CP (5 to 8 years old) underwent an intensive one-week-long nonremovable hard-constraint CIMT. Before and directly after the treatment, we recorded their cortical event-related potential (ERP) responses to calibrated light touch (versus a ...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
Conclusions: This is the largest cohort of HPeV3 cases with clinical data and pediatrician-assessed neurodevelopmental follow-up to date. Developmental concerns were identified in 11 children at early follow-up. Abnormal magnetic resonance imaging during acute infection did not specifically predict poor neurodevelopmental in short-term follow-up. Continued follow-up of infants and further imaging correlation is needed to explore predictors of long-term morbidity.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
Source: European Journal of Physiotherapy - Category: Rehabilitation Authors: Source Type: research
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