Is there any analgesic benefit from preoperative vs. postoperative administration of etoricoxib in total knee arthroplasty under spinal anaesthesia?: A randomised double-blind placebo-controlled trial

CONCLUSION: Preemptive administration of etoricoxib 120 mg orally in patients undergoing total knee arthroplasty under spinal anaesthesia is superior to postoperative administration of the same dose in terms of its morphine-sparing effect during the first postoperative 48 h, but not in prolonging the time to first analgesia, and is associated with a similar incidence of side-effects. TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT 02534610.
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Pain Source Type: research

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This study is an attempt to investigate the effects of intrathecal administration of Melissa officinalis on the pain induced by heat and formalin.In this experimental study, seventy male Wistar rats with an average weight of 270-320 g were randomly divided into 5 groups: control; sham, that received 25 μl of saline through the spinal catheter; and three experimental groups, that received 5, 10 or 20 mg/kg Melissa officinalis via the spinal catheter respectively. Five days after catheterization of the spinal cord from the lumbar region under anesthesia, the effects of Intrathecal administration of Melissa officinalis on ...
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
CONCLUSION: Men with rectal prolapse were younger, healthier, and had relatively better anorectal function than women. The Delorme-Thiersch operation in men promoted lower recurrence rates and was advantageous in preserving the fertility of young patients, but the incidence of complications was also higher in men. Adequate counseling and preparation for the possibility of complications are needed. PMID: 31726002 [PubMed]
Source: Annals of Coloproctology - Category: Gastroenterology Tags: Ann Coloproctol Source Type: research
Conclusions68% of all the patients obtained good pain tolerance through anal anesthetic block, females manifested better pain tolerance than males, in non-complicated anorectal pathology local block ha shown to be safe and reproductible for the treatment of benign anorectal pathology in the Guatemalan Institute for Social Security.ResumoIntroduçãoO uso de bloqueio anestésico regional aumentou ao mesmo tempo em que diminuiu o uso do anestésico espinhal nesse campo específico da atividade cirúrgica. Na última década, a cirurgia ambulatorial e o anestésico local a...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
The phrase “sacred masculine” can evoke images of patriarchal religiosity.  But it has a different meaning for today’s guest. For Miguel Dean, the sacred masculine is an ideal, embodied by a man who accepts all of his emotions, understands the connectedness of humanity, and is devoted to helping others. Join us as Miguel explains how the sacred masculine is increasingly being recognized as a new model of masculinity to replace the old ideas of what it meant to be a man. This new man embraces all of his humanity and recognizes that part of this is the courage to feel, express and honor the full spect...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Ethics & Morality General Inspiration & Hope Interview LifeHelper Men's Issues Podcast Relationships Self-Help Spirituality The Psych Central Show Source Type: blogs
Police officer Charles Thomas (left) examines an Esmarch chloroform mask (similar to the museum example,right) found in November of 1933 alongside the dead body of Chicagoan Rheta Wynekoop. As the latter ’s philandering husband rode a train out of town, his cash-strapped mother, physician Alice Wynekoop (1871 to 1955), confirmed that she had already taken out extra life insurance on Rheta. When Rheta complained of abdominal pain, her mother-in-law chloroformed her “for the examination.” Panick ing when Rheta appeared to have dropped dead, Dr. Wynekoop tried to cover up the medical mishap by shooting her d...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
While living abroad, the former First Lady of the United States, Mrs. Mary Todd Lincoln (1818 to 1882) tried to realign a picture hanging in her parlor in Pau, France. Unfortunately, the chair that she was standing upon collapsed, throwing her against a table. Debilitated by the ensuing back pain, Mrs. Lincoln boarded a transatlantic steamer back to New York City in October of 1880. There she was nearly crushed, emotionally and physically, by crowds rushing past her toward fellow passenger, actress Sarah Bernhardt. As the impoverished Mrs. Abraham Lincoln lingered in New York, waiting for congressional supplementation of h...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Conclusions: Spinal anesthesia with a median or paramedian approach at cesarean section has no effect on the incidence of PDPH, but we believe that there has been a need for further studies with larger or different patient populations.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
Conclusions68% of all the patients obtained good pain tolerance through anal anesthetic block, females manifested better pain tolerance than males, in non-complicated anorectal pathology local block ha shown to be safe and reproductible for the treatment of benign anorectal pathology in the Guatemalan Institute for Social Security.ResumoIntroduçãoO uso de bloqueio anestésico regional aumentou ao mesmo tempo em que diminuiu o uso do anestésico espinhal nesse campo específico da atividade cirúrgica. Na última década, a cirurgia ambulatorial e o anestésico local a...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
Authors: Chaudhary B, Tripathy PR, Gaikwad MR Abstract Vertebral artery is a branch of 1st part of subclavian artery. Vertebral artery arising from the aortic arch most commonly presents on the left side. The cervical part of sympathetic trunk is closely related to the vertebral artery in the cervical region. Though lots of variations regarding anomalous origin, course of vertebral artery is reported in the literature, here we present a rare anomaly in which vertebral artery after originating from aortic arch is passing through stellate ganglia and it enters into the transverse foramina of higher cervical vertebra ...
Source: Folia Morphologica - Category: Anatomy Tags: Folia Morphol (Warsz) Source Type: research
Thoracic injuries present many challenges for management in the acute and inpatient settings, including achieving appropriate pain control. Traditional modalities, such as opioids and spinal epidural anesthesia, are associated with multiple complications. Ultrasound-guided regional nerve blocks are becoming more prevalent, and they have been shown to be an effective modality of pain control for other traumatic injuries. Models comprised of animal tissue to simulate human anatomy are widely utilized to facilitate training of needle-guided procedures, but no such model for the serratus anterior plane block has yet been defin...
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Ultrasound in Emergency Medicine Source Type: research
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