Neurobasal media facilitates increased specificity of siRNA-mediated knockdown in primary cerebellar cultures

Conclusions Specific knockdown of target can be achieved in primary cerebellar granule cells using Accell siRNAs in Neurobasal™ media. This method ensures specific knockdown in post-mitotic neurons without the need for biosafety level 2 laboratories, additional reagents, or instruments needed by other transfection
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research