Incidence and predictors of stroke during the index event in an ethnically diverse Takotsubo cardiomyopathy population.

Incidence and predictors of stroke during the index event in an ethnically diverse Takotsubo cardiomyopathy population. Funct Neurol. 2016 Jul-Sep;31(3):157-62 Authors: Dias A, Franco E, Janzer S, Koshkelashvili N, Bhalla V, Rubio M, Amanullah S, Hebert K, Figueredo VM Abstract Takotsubo cardiomyopathy (TTS) is a peculiar clinical condition often affecting postmenopausal women after a stressful trigger. The underlying mechanisms have not been completely elucidated but several hypotheses have been advanced, with catecholamine cardiotoxicity, microvascular dysfunction and coronary artery spasm each suggested to play a role. The incidence of stroke after TTS appears to range from 0% to 7.7%, and interestingly TTS has been described as both a cause and a complication of stroke. We sought to assess the incidence and predictors of stroke during the index event (peri-index event stroke) in a heterogeneous TTS population. We conducted a retrospective descriptive study reviewing patients who were discharged with a diagnosis of TTS from the Einstein Medical Center, Philadelphia, PA and Danbury Hospital, Danbury, CT in the period between 2003 and 2014. A total of Incidence and predictors of stroke during the index event in an ethnically diverse Takotsubo cardiomyopathy population 206 patients met the modified Mayo Clinic criteria and were included in the study. The patients' overall mean age was 67.8 years; 87% (n=179) were females and 25% (n=5...
Source: Functional Neurology - Category: Neurology Tags: Funct Neurol Source Type: research