Reporting of Acute Flaccid Paralysis in Children under 15 years of age: Improving Surveillance, January 2009 - December 2014.

Reporting of Acute Flaccid Paralysis in Children under 15 years of age: Improving Surveillance, January 2009 - December 2014. Ir Med J. 2016;109(2):357 Authors: Flanagan P, O'Lorcain P, Cotter S, Connell J, Lynch B, Cunney R, O'Flanagan D Abstract Acute Flaccid Paralysis (AFP) surveillance, including case investigation and specimen collection is a gold standard method for poliomyelitis surveillance. The expected annual non-polio AFP rate
Source: Ir Med J - Category: Journals (General) Authors: Tags: Ir Med J Source Type: research

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Carter Roberts’ motorized wheelchair didn’t arrive until the day he died. It had been a long time coming and his parents had fought hard to get it. The chair cost more than $32,000 and the insurance companies wouldn’t cover it, so the family went to court. One insurer eventually agreed to pay for some components of the chair but not the whole thing. And then none of it mattered anyway. On Sept. 22, 2018, the Roberts’ doorbell rang and the chair was delivered. Also on Sept. 22, 2018, Carter died, just three months shy of his sixth birthday. He had been largely paralyzed for the final two years of his...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Infectious Disease viruses Source Type: news
Conclusion: This review presents the current knowledge on acute flaccid myelitis with respect to the clinical presentation and its differential diagnosis with Guillain-Barr é syndrome and acute transverse myelitis. We also discuss the association with enterovirus D68 and the presumed pathophysiological mechanism of this infection causing anterior horn cell damage. Sharing clinical knowledge and insights from basic research is needed to make progress in diagnosis, trea tment, and prevention of this new polio-like disease.What is Known:•Acute flaccid myelitis (AFM) is a polio-like condition characterized by rapid...
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
To the Editor We read with great interest the retrospective case analysis by Elrick et al titled “Clinical Subpopulations in a Sample of North American Children Diagnosed With Acute Flaccid Myelitis, 2012-2016” regarding the definition of more specific diagnostic criteria for acute flaccid myelitis (AFM). We concur with the authors in that the standardized case definition of AFM as adopted by the US Centers for Disease Control and Prevention after the 2014 epidemic is appropriately sensitive in capturing possible AFM cases for epidemiologic surveillance. However, other neurologic entities that cause acute limb ...
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research
This study describes AFP surveillance in Spain from 1998 to 2015. During this time, 678 AFP cases were reported to the Spanish National Surveillance Network. The mean notification rate was 0.58 AFP cases/100,000 population under 15 years old (range: 0.45/100,000-0.78/100,000). Two periods (P) are described: P1 (1998-2006) with the AFP notification rate ranging from 0.66/100,000 to 0.78/100,000, peaking in 2001 (0.84/100,000); and P2 (2007-2015) when the AFP rate ranged from 0.43/100,000 to 0.57/100,000, with the lowest rate in 2009 (0.31/100,000). No poliomyelitis cases were caused by wild PV infections, although two Sabin...
Source: Euro Surveill - Category: Infectious Diseases Authors: Tags: Euro Surveill Source Type: research
Conclusions: True association of the disease withCampylobacter spp. will enable the proportion ofCampylobacter-induced GBS to be better described in South Africa; this can only be done through systematic studies that include bacterial culture and serology together with molecular methodologies.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research
Discussion Leg pain in children has a broad differential diagnosis and includes more innocuous problems such as growing pains and transient synovitis but also more serious problems including neurological diseases or malignancy. Occult or self-limited trauma are also common causes. A review can be found here. Limping can be painful or painless and has its own differential diagnosis which can overlap with leg pain. A differential diagnosis for limping can be found here. Muscle weakness also has its’ own differential diagnosis which can be found here. Learning Point Benign acute childhood myositis (BACM) has other names...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Serological Markers of Recent Campylobacter jejuni Infection in Patients with Guillain-Barré Syndrome in the State of Piauí, Brazil, 2014-2016. Am J Trop Med Hyg. 2018 Jan 08;: Authors: Souza CO, Vieira MACS, Batista FMA, Eulálio KD, Neves JMM, Sá LC, Monteiro LCR, Almeida-Neto WS, Azevedo RSS, Costa DL, Cruz ACR Abstract In countries where poliomyelitis has been eradicated, Guillain-Barré syndrome (GBS) is the leading cause of acute flaccid paralysis. The range of infections that precede GBS in Brazil is unknown. Campylobacter jejuni infection is the most frequent t...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
We report a case of acute segmental flaccid paralysis with respiratory involvement in an adult in the UK, with enterovirus D68 detected in a sputum sample. MR imaging of cervical spinal cord showed a longitudinally extensive T2 hyperintensity in the anterior cord. Cerebrospinal fluid showed an elevated white cell count, predominantly lymphocytic, with otherwise normal constituents and negative viral PCRs. His respiratory function improved after intravenous immunoglobulin, suggesting that this may be useful in such cases. Clinicians should consider enterovirus D68 infection in the differential diagnosis of Guillain-Barr&eac...
Source: Practical Neurology - Category: Neurology Authors: Tags: Pract Neurol Source Type: research
World Health Organization. 01/23/2017 This Web page provides information about how the World Health Organization is exploring using the existing infrastructure for surveillance of polio to detect people with Zika and related neurological complications in a cost-effective way. It discusses topics that include the link between Zika and polio, how the polio surveillance system could help detect Zika virus outbreaks, and if the polio surveillance system could help estimate Guillain-Barr é syndrome trends. (Text)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: Global & Universal Authors: Source Type: news
A century after it was first described, Hugh Willison and colleagues (Aug 14, p 717) provide a fabulous clinical overview of advances in the pathophysiology, immunopathology, and management of Guillain-Barr é syndrome.1 Unfortunately, despite listing poliomyelitis in their differential diagnosis, no mention was made of the global public health surveillance importance of Guillain-Barré syndrome.
Source: LANCET - Category: Journals (General) Authors: Tags: Correspondence Source Type: research
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