Primary orbital synovial sarcoma: a clinicopathologic review with a differential diagnosis and discussion of molecular genetics
Synovial sarcoma (SS) is a soft tissue sarcoma of the extremities developing in young adults that has rarely been reported in the orbit. SS is associated with a unique translocation, resulting in an SYT-SSX fusion gene. We analyze seven published periocular cases, together with the current one, to gain a better appreciation of the features of the tumor in this location and to compare the findings with those derived from non-ophthalmic studies. A 31-year-old woman developed an inferior orbital mass after experiencing periorbital and hemifacial pain for more than a decade.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Anna M. Stagner, Frederick A. Jakobiec, Aaron Fay Source Type: research
More News: Genetics | Opthalmology | Pain | Sarcomas | Soft Tissue Sarcoma | Study | Synovial Sarcoma | Translocation