Managing and Mitigating the Health Risks of Climate Change: Calling for Evidence-Informed Policy and Action

Discussion Human health is already affected by climate change, and its effects will increase over time. In the longer term, a greater health hazard for many populations will arise from disturbances to environmental, ecological, and social living conditions. As the protection and improvement of human health is one of the ultimate goals of sustainable development, epidemiologists and public health professionals should play an active role in the development of plans for reducing the adverse health effects of climate change at national, regional, and international levels, just like the phasing out of lead from gasoline and taking actions to slow down stratospheric ozone depletion. Based on the accruing evidence, we make the following policy recommendations: True primary prevention of adverse climate change impacts on human health (along with many other aspects of the biophysical world) requires a significant worldwide reduction in greenhouse gas emissions, which is possible to achieve with present technology. It is encouraging that the international community recently agreed to curb their greenhouse gas emissions over the coming decades and to limit global temperature rise to
Source: EHP Research - Category: Environmental Health Authors: Tags: Brief Communication October 2016 Source Type: research

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Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00126K, CommunicationHiromichi Egami, Satoshi Nakagawa, Yuki Katsura, Masakatsu Kanazawa, Shingo Nishiyama, Toshihiro Sakai, Yasushi Arano, Hideo Tsukada, Osamu Inoue, Kenichiro Todoroki, Yoshitaka Hamashima Dihydromethidine (DHM) labeled with 18F at the para position of the benzene ring was designed as a positron emission tomography (PET) radiotracer for non-invasive imaging of reactive oxygen species (ROS).... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
Publication date: Available online 15 February 2020Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Manal Naciri, Yasmina El Aoufir, Hassane Lgaz, Fatima Lazrak, Ahmed Ghanimi, Abdallah Guenbour, ismat H. Ali, Mouloud El Moudane, Jamal Taoufik, Ill-Min ChungAbstractCarbon steel is a commonly used alloy in petroleum refining equipment. Nonetheless, its weak corrosion resistance is a perpetual problem for these industries. In the present study, we manifest the usefulness of a novel 1,2,4-triazole derivative, namely 5-hexylsulfanyl-1,2,4-triazole (HST) in inhibiting the carbon steel (CS) corr...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
Publication date: Available online 15 February 2020Source: Journal of Hazardous MaterialsAuthor(s): Fisseha A Bezza, Shepherd M Tichapondwa, Evans MN ChirwaAbstractUniformly dispersed silver nanoparticles (AgNPs) with remarkable colloidal stability were synthesized using chemical reduction method in lipopeptide biosurfactant reverse micelles. Transmission Electron microscopy (TEM), Scanning electron microscopy (SEM) and UV–vis spectroscopy analysis exhibited monodisperse nanoparticles with spherical morphology of diameter of 21 ± 2. The lipopeptide stabilized AgNPs displayed remarkable antibacter...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
ConclusionsNatalizumab is highly effective as measured by the NEDA long-term remission parameter.ResumenIntroducciónLa efectividad y seguridad de natalizumab en pacientes con esclerosis múltiple remitente recurrente (EMRR) se demostró en ensayos clínicos. Sin embargo, por las limitaciones de estos, es importante saber cómo se comporta en condiciones de práctica clínica a largo plazo.ObjetivoConocer la eficacia a largo plazo de natalizumab en pacientes con EMRR mediante la evaluación anual del NEDA (no evidence of disease activity), que incluye número de brotes,...
Source: Neurologia - Category: Neurology Source Type: research
AbstractThis guideline aims to describe the complement system and the functions of the constituent pathways, with  particular focus on primary immunodeficiencies (PIDs) and their diagnosis and management. The complement system is a crucial part of the innate immune system, with multiple membrane-bound and soluble components. There are three distinct enzymatic cascade pathways within the complement system, the classical, alternative and lectin pathways, which converge with the cleavage of central C3. Complement deficiencies account for ~5% of PIDs. The clinical consequences of inherited defects in the complement system...
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
AbstractAerophagia is a functional gastrointestinal disorder characterized by excessive swallowing of air associated with abdominal distension and pain, flatulence, belching, nausea, and vomiting. The purpose of the current study was to evaluate the effectiveness of an antecedent-based behavioral intervention on aerophagia with an adolescent female diagnosed with Lennox-Gastaut syndrome (LGS), severe intellectual disability, and herpes simplex virus infection of the central nervous system with chronic static encephalopathy. Results from a functional analysis and multiple-component aerophagia assessment suggested that aerop...
Source: Journal of Developmental and Physical Disabilities - Category: Disability Source Type: research
AbstractThe Vi polysaccharide typhoid fever vaccine (TFV) provides incomplete protection against typhoid fever. BCG, the vaccine against tuberculosis, can potentiate immune responses to other vaccines through induction of trained innate immunity and heterologous adaptive immunity. We performed an explorative, randomized, noncontrolled open trial to investigate whether BCG vaccination increases humoral and cellular response to TFV and whether BCG and TFV modulate nonspecific immune responses. Thirty volunteers were randomized to receive either TFV alone or BCG followed by TFV after 2  weeks. Ex vivo leukocyte responses...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Publication date: Available online 16 February 2020Source: International Journal of PharmaceuticsAuthor(s): Namita P. Tipnis, Jie Shen, Derek Jackson, Daniel Leblanc, Diane J. BurgessAbstractThe main objective of the current research was to develop a compendial flow-through cell apparatus based in vitro release testing method for sustained-release triamcinolone acetonide–loaded poly (lactic-co-glycolic) acid (PLGA) microspheres. Media-based and instrument-based parameters, such as surfactant type, concentration, media volume, flow rate, and testing temperature, were investigated. In addition, a detailed exploration w...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Conclusions: This retrospective registry-based study provides a picture of CIED first implants in HCM patients in a Swedish tertiary university hospital. ICDs were the most commonly implanted devices, covering 59% of CIED implants. HCM patients receiving a pacemaker or an ICD had different epidemiological and clinical profiles. PMID: 32054352 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
ConclusionsThe variability of radiocholine uptake in adrenal glands depends probably on overall body metabolism and hypophyseal function expressed by statistically significant correlation with liver and pituitary gland uptake.Predominant focal or mixed with focal areas uptake patterns on positron emission tomography in normal in computed tomography adrenal glands should be assessed with caution to avoid a diagnostic mistake.
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
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