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Ibuprofen-like painkillers linked to an increased risk of heart failure

Conclusion This useful and well-conducted study isn't the first to say NSAIDs may raise the risk of heart failure. We've known for some time that NSAIDs can have side effects, especially when used at high doses and for long periods. What this study does help show is the different levels of risk between different NSAIDs, and confirms that the risk depends partly on the dose. It's important to remember that the study only included people who were prescribed NSAIDs and not people who'd bought them over the counter. The information is most useful to older people taking prescribed NSAIDs long-term for conditions such as gout or arthritis. These are the people most likely to be affected by heart problems linked to NSAIDs. The study shows that some NSAIDs are less risky than others, and doctors can use this information to discuss with patients which is the most suitable drug if they need long-term anti-inflammatory painkillers. For people who take NSAIDs over the counter, it's a reminder that these drugs are not risk-free. While an otherwise healtlhy 20-something taking ibuprofen for a day or two to get over backache is highly unlikely to get heart failure as a result, long-term use of NSAIDs at high doses can cause problems. Sensible advice is to take the lowest dose that works for the shortest period you need it. If you find you need to take NSAIDs very often, or you're taking doses higher than those recommended, you should talk to your doctor ab...
Source: NHS News Feed - Category: Consumer Health News Tags: Medication Heart/lungs Source Type: news

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People who undergo root canals may soon have a tiny but powerful ally that could prevent infection after treatment.Researchers at theUCLA School of Dentistry and theUCLA Henry Samueli School of Engineering and Applied Science found in a clinical trial that nanodiamonds protected disinfected root canals after the nerve and pulp were removed, thereby improving the likelihood of a full recovery. The findings are a milestone for the use of nanodiamonds in humans.Nanodiamonds are tiny particles made of carbon and are so small that millions of them could fit on the head of a pin. They resemble soccer balls but have facets like a...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Conclusion: Very limited evidence to support recreational activity and walking intervention was found for knee osteoarthritis, in the short-term on pain and physical function, respectively.
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Original Research Articles Source Type: research
Conclusions: In relieving pain and improving self-report function, PRP showed no superiority over hyaluronic acid in well-designed double-blind trials, and beneficial effects of PRP in most trials probably resulted from insufficient blinding methods. However, PRP is still considered more effective than placebo on the basis of present evidence.
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Original Research Articles Source Type: research
Abstract: A 13-yr-old adolescent boy presented with wrist pain after falling off a scooter onto his outstretched hand. Radiographs revealed a nondisplaced hairline fracture of the scaphoid bone and an irregular radiolucent line in the proximal metaphysis of the second metacarpal bone, consistent with an anomalous growth plate, or complete pseudoepiphysis. Complete pseudoepiphysis is a rare finding, with only a few cases reported. Learning about the common locations of growth plates and the radiographic differences between normal, injured, and anomalous growth plates can help decrease physician error and improve patient outcomes.
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Case Reports Source Type: research
In this report, a paraparetic patient who has ochronotic spondiloarthropathy with the presence of HLA B27 antigen is described. He had low back and leg pain and morning stiffness for 5 yrs. Last year, these were followed by tingling, numbness, and weakness the in lower extremities and he was operated on with preliminary diagnosis of prolapsed disc herniation and cord compression. Surgery is suggested for disc herniations related to ochronotic spondyloarthropathy if it is necessary or neurologic symptoms are present. However, his pain and weakness have partially recovered after the operation. After medical and physical trea...
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Case Reports Source Type: research
No abstract available
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Visual Vignettes Source Type: research
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Statin use seems to further increase the risk for diabetes in patients already at high risk, according to a secondary analysis in BMJ Open Diabetes …
Source: Physician's First Watch current issue - Category: Primary Care Source Type: news
A new analysis of the DPP provides further evidence that long-term statin use ups the risk of diabetes -- in this case, in individuals already at high risk, by around 30%.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
STATINS increase the risk of developing Type 2 diabetes by a third, new research suggests.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The US cesarean delivery rate remains 30%–32%. Increases in maternal age, obesity, and diabetes put upward pressure on this rate. Alternatives to cesarean delivery, vaginal birth after cesarean (VBAC), and operative vaginal delivery, are underutilized and there are substantial challenges to their resurgence. Practice guidelines offer promise, but demonstrate only minor reductions in cesarean delivery. We estimate that the overall rate in the US will remain 27%–30% for the immediate future. As more states move to recognize the independent practice of midwifery and more payers seek lower cost options for childbir...
Source: Clinical Obstetrics and Gynecology - Category: OBGYN Tags: Future of Obstetrical Care Source Type: research
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