24 Creative Geniuses Who Inspire Boldness (Even if You ’re Shy or Socially Anxious)

You're reading 24 Creative Geniuses Who Inspire Boldness (Even if You’re Shy or Socially Anxious), originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. “Any step in the direction of expressing your creative impulses is a step in the direction of actualizing the genius that resides within you.” -Dr. Wayne Dyer Genius? Expressing creative impulses? Isn’t that aiming a little high? I’m just trying to survive. If this represents the tired record playing in your mind, stick around for some major inspiration. Perfection on the outside, with a sense of burning loneliness or numbness on the inside, is a dead-end approach.  It will sap your energy and leave a big hole in your life and heart. You get this. Do you hesitate when something new or exciting presents itself? You might tell yourself you tried before and failed, you don’t know how, or you'll look stupid. Imagine you couldn't fail with others, what would you do? Make friends and find love. Have fun at social events. Not assume you are the problem. Enjoy speaking with interesting people. Say yes to your purpose. Get so good at failing you succeed. Maybe you would simply be yourself and forget the rest. But how do you get there? You don’t do it by masking your feelings or scaring yourself.   Instead of putting up a wall and carrying the weight of the world on your...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: confidence creativity featured self improvement best inspirational quotes best self-improvement blogs creative genius how to be bold how to build confidence pickthebrain self confidence Source Type: blogs

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We report a successful case of hepatic ductoplasty combined with hepaticojejunostomy (H-J) for the treatment of iatrogenic Bismuth type 2 stricture.Presentation of caseThe patient was a 68-year-woman who had undergone choledochojejunostomy (C-J) 6 years earlier due to bile duct injury after laparoscopic cholecystectomy for cholelithiasis. She complained of recurrent chills and upper back pain. Cholangiography and computed tomography revealed a C-J anastomotic stricture with hepatolithiasis. The diagnosis was reflux cholangitis with hepatolithiasis due to C-J stricture and a fistula between the reconstructed jejunal limb an...
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionSurgeons must have high index of suspicion for elderly obese males with inguinal hernias and urinary or intestinal obstruction symptoms. Careful preoperative planning must be made to avoid repair associated bladder injuries.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Abstract To clarify the morphology effect of metal-organic frameworks (MOFs) on their electrochemistry as well as to explore their electrochemical applications, three MOFs with metal centers of nickel, cobalt, and zinc are synthesized. The used organic ligand is only 1,3,5-benzenetricarboxylic acid. Characterizations using Fourier Transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and electrochemical techniques reveal that these MOFs possess similar bonding properties, crystalline structures and phase purity, but various morphology and electrochemical activities, including their own ...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Abstract Herein, a novel class-specific artificial receptor-based on molecularly imprinted polymer (MIP)-coated quantum dots (QDs@MIP) was synthesized, characterized, and used for the detection and quantification of the bacterial quorum signaling molecules N-acyl-homoserine lactones (AHLs), a class of autoinducers from Gram-negative bacteria. The QDs@MIP was prepared by surface imprinting technique under controlled conditions using CdSe/ZnS QDs as the signal transducing material. The synthesis of the QDs@MIP was characterized by transmission electron microscopy, scanning electron microscopy, Fourier transform infr...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Abstract Natural medicinal substances (NMS) have great inconsistency due to chemical variability, seriously limiting their development as therapeutics. Here, we chose toad venom with anti-tumor activities as a model and developed a pipeline of metabolomics-based screening and quality consistency control (MSQCC) as one potential solution to this long-standing problem. Our study firstly exemplified the power of the co-correlation screen of metabolomic and biological profiles of 180 fractions prepared from natural heterogeneous venom samples, to identify a series of bufadinolides as quality control markers for cancer...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
ka P, Prokopec V, Švecová M Abstract Recent advances in nanotechnology have opened a lot of new possibilities for nanomaterials application in wide variety of industrial, pharmaceutical, medicinal and environmental applications. This review aims to description of various Fourier Transform Infrared (FTIR)-based spectroscopic techniques suitable to characterize (i) different types of nanomaterials and (ii) various macroscopic samples at their nanoscale. In the introductory section, nanomaterials are classified according to their crucial properties, i.e. chemical composition, size and surface morphology...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Paeoniflorin inhibits IL-1β-induced MMP secretion via the NF-κB pathway in chondrocytes. Exp Ther Med. 2018 Aug;16(2):1513-1519 Authors: Hu PF, Sun FF, Jiang LF, Bao JP, Wu LD Abstract Paeoniflorin serves important cellular roles, exerting anti-cancer, anti-inflammatory and anti-pulmonary fibrosis effects and possesses immune-modulatory properties. However, the exact role of paeoniflorin in the pathogenesis of osteoarthritis (OA) remains unclear. The aim of the present study was to investigate the effects of paeoniflorin on articular surfaces in vitro. Rat chondrocytes were cultured in vitro...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Zhang M, Liu J, Li M, Zhang S, Lu Y, Liang Y, Zhao K, Li Y Abstract Glioblastoma multiforme (GBM) is a malignant tumor caused by complex pathological mechanisms, and is characterized by a high rate of cancer-related mortality and poor patient prognosis. Overgrowth of cancer cells, which results from the inhibition of cell apoptosis and/or the promotion of cell proliferation, leads to the progression of GBM. Therefore, studies into the regulatory mechanisms of cancer cell growth in GBM are required to identify potential therapeutic targets and improve treatment for GBM. In the present study, the role of ins...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Zhang X, Chen L Abstract Renal cell carcinoma (RCC) and chronic kidney disease (CKD) are associated with hypoxia, but the effects of hypoxia on the process of angiogenesis in the two diseases are dramatically different. Some of matrix metalloproteinases (MMPs), such as MMP2 and MMP9, may have a role because they represent the most prominent family of proteinases associated with angiogenesis. In the present study, the differential response of human renal cell cancer cells (786-0), human renal tubular epithelial cells (HK-2) and human microvascular endothelial cells (HMEC-1) to hypoxia with regards to the ex...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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