Identification of genetic variation in the lncRNA HOTAIR associated with HPV16-related cervical cancer pathogenesis

ConclusionsOur data indicate that rs2366152C not only has the potential to serve as a marker for singling out CaCx cases lacking metastatic molecular signatures, but also to explain the functional inactivation of HOTAIR in these cases, including the mechanism of its down-regulation.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research