Clinical and Imaging Signs of Spondyloarthritis in First ‐Degree Relatives of HLA–B27–Positive Ankylosing Spondylitis Patients: The Pre‐Spondyloarthritis (Pre‐SpA) Cohort Study

ConclusionA substantial proportion of seemingly healthy first‐degree relatives of HLA–B27–positive AS patients have clinical and/or imaging abnormalities suggestive of SpA. Thirty‐three percent could be classified as having SpA. Further follow‐up will show which first‐degree relatives will develop clinically manifest SpA.

Source: Arthritis and Rheumatism - September 27, 2016 Category: Rheumatology Authors: Maureen C. Turina, Janneke J. de Winter, Jacky E. Paramarta, Mihaela Gamala, Nataliya Yeremenko, Marita N. Nabibux, Robert Landew é, Dominique L. Baeten Tags: Spondyloarthritis Source Type: research