Does high-dose Botulinum Toxin has a Better Effect than Lower Dose in Spasticity Managements When given Early After Stroke

1)To evaluate the clinical effects of treatment with a higher dose (up to 600 U) , versus a lower dose (up to 200 U) of botulinum toxin.That will be injected early after stroke, when compared with placebo, in the treatment of upper limbs spasticity after stroke. 2)To evaluate the clinical effects of early treatment with a higher dose (up to 600 U) versus a lower dose (up to 200 U) of botulinum toxin on upper limb function recovery after stroke. 3) To asses the effect of early Botulinum Toxin injection on pain reduction post-stroke.

Source: Archives of Physical Medicine and Rehabilitation - September 27, 2016 Category: Rehabilitation Authors: Abathar Aladi Source Type: research