Drug-Resistant Gonorrhea Strain In Hawaii A First For U.S.

A drug-resistant cluster of gonorrhea infections in Hawaii have health officials worried that the sexually transmitted disease could soon prove untreatable. The Centers for Disease Control and Prevention announced this week that an antibiotic-resistant strain was discovered earlier this year in seven patients in Honolulu. All the individuals ― six men and one woman ― were successfully treated using the CDC-recommended two-drug combination of ceftriaxone and azithromycin. Laboratory tests, however, showed the strain had “decreased susceptibility to ceftriaxone and very high-level resistance to azithromycin,” according to the CDC. It marks the first time a cluster of infections in the U.S. has been shown to resist the last line of defense. Dr. Alan Katz, a professor of public health at the University of Hawaii, told The Huffington Post it’s important to understand that gonorrhea, at least for now, is still treatable ― that this potenial “superbug” has not yet arrived.  What has Katz and others worried is that the strain could continue mutating. “If it develops more resistance, then it can potentially become a problem,” Katz said. The Hawaii discovery comes just two months after a CDC report warned about the looming threat of drug-resistant Neisseria gonorrhoeae ― the bacteria that causes gonorrhea ― and the World Health Organization released new guidelines for treating the STD. “Our last line of ...
Source: Science - The Huffington Post - Category: Science Source Type: news

Related Links:

In conclusion, HlMeOHe damaged the liver with an oral dose of 200 mg/kg, and at 1000 mg/kg injured the kidneys and pancreas of the CD-1 male mice. PMID: 29923593 [PubMed - as supplied by publisher]
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
CONCLUSIONS: Data suggest KISS1 as a great candidate for CC molecular markers or as a therapeutic target for CC. Also, HPV presence does not seem to alter the KISS1 expression in CC. PMID: 29914007 [PubMed - as supplied by publisher]
Source: Cancer Biomarkers - Category: Cancer & Oncology Tags: Cancer Biomark Source Type: research
Authors: Wang S, Cui S, Zhao W, Qian Z, Liu H, Chen Y, Lv F, Ding HG Abstract BACKGROUND: Circular RNAs (circRNAs) play an important role in pathogenesis and development of hepatocellular carcinoma (HCC). However, circRNA expression profiles in hepatitis B Virus (HBV)-related HCC remain to be studied. METHODS: Total 13 HBV-related HCC patients were enrolled for study. Three HCC and 3 paired adjacent non-tumorous (NT) tissues from 3 patients were performed for microarray. Ten pairs of HCC tissues were used to verify the identified up-regulated and down-regulated circRNAs obtained from the microarr...
Source: Cancer Biomarkers - Category: Cancer & Oncology Tags: Cancer Biomark Source Type: research
Authors: Guan J, Singh-Mallah G, Liu K, Thorstensen E, Shorten P, Mitchell EA, Taylor R, Harris P, Brimble M, Thompson JMD, Murphy R Abstract Cyclic Glycine-Proline (cGP) regulates the homeostasis of insulin-like growth factor (IGF)-1 function and cGP/IGF-1 ratio determines IGF-1 bioactivity in vitro and in vivo. Plasma IGF-1 represents largely inactive IGF-1 and weakly associated with human obesity and hypertension. We evaluated the regulatory role for cGP in pregnancy-related obesity and hypertension, and in obesity status between pregnancy and postpartum. Women were recruited in their first pregnancy. A cross-se...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Source: BMJ - Category: General Medicine Source Type: research
A Swedish study, published inBJOG: An International Journal of Obstetrics& Gynaecology, reports that those diagnosed with PCOS are more likely to have obese mothers or mothers that smoked during pregnancy.Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
[This Day] While one in every four Nigerian couples experience delay in achieving conception, experts say with multiple IVF the challenge can be addressed. Martins Ifijeh chronicles the lives of couples who through the assisted reproductive technology are now proud parents.
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
There is not enough evidence to recommend women take vitamin D supplements during pregnancy to help avoid high blood pressure or pre-eclampsia, according to a major new study.
Source: Nursing Times - Category: Nursing Source Type: news
We present a case of Nivolumab-induced adrenal insufficiency in a man who complained of refractory hypotension. A 52-year-old man with non-small cell lung cancer visited our emergency department complaining of fatigue and diarrhea. He had received Nivolumab every 2 weeks as third-line therapy for a total of 10 times. On arrival, his vital signs revealed shock: blood pressure, 68/48 mmHg; heart rate, 141 beats per minutes. Laboratory examination showed severe hemoconcentration with a hemoglobin level of 19.9 g/dL, normal electrolyte levels and hyperglycemia. We started intravenous infusion of 4.5 L of extracellular fluid, b...
Source: Nagoya Journal of Medical Science - Category: International Medicine & Public Health Tags: Nagoya J Med Sci Source Type: research
Authors: Tien Dat T, Kotani T, Yamamoto E, Shibata K, Moriyama Y, Tsuda H, Yamashita M, Kajiyama H, Duc Thien Minh D, Quang Thanh L, Kikkawa F Abstract Dengue fever during pregnancy is an expanding issue in Southeast Asia; however, the knowledge of adverse effects on mothers and neonates remains limited. Therefore, we aimed to determine the impact of dengue fever. The clinical information of 20 patients of dengue fever during pregnancy in Vietnam from January 1, 2015 to December 31, 2015 was collected and their outcomes were retrospectively investigated. A total of 18 patients (90%) presented with positivity of non...
Source: Nagoya Journal of Medical Science - Category: International Medicine & Public Health Tags: Nagoya J Med Sci Source Type: research
More News: Azithromycin | Ceftriaxone | Centers for Disease Control and Prevention (CDC) | Clinical Trials | Conferences | Health | Hepatitis | HIV AIDS | Infectious Diseases | Infertility | International Medicine & Public Health | Laboratory Medicine | Penicillin | Pregnancy | Reproduction Medicine | Rocephin | Science | STDs | Superbugs | Tetracycline | Websites | WHO | Women | Zithromax