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Katie Prager, wife in real 'Fault in Our Stars' couple, dies

Katie Prager, the wife in the real "Fault in Our Stars" couple, died Thursday after complications from cystic fibrosis and a lung transplant. She was 26 years old.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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Conclusion: IT following lung and liver transplantation, with injection of islets into a transplanted organ, is feasible. It improves C-peptide secretion, decreases insulin needs, and lowers HbA1c.Horm Res Paediatr
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research
Condition:   Lung Transplant Rejection Intervention:   Device: photopheresis Sponsors:   Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico;   Italian Cystic Fibrosis Research Foundation Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Abstract The repurposing of drug delivery by the pulmonary route has been applied to treatment and prophylaxis of an increasingly wide range of respiratory diseases. Repurposing has been most successful for the delivery of inhaled bronchodilators and corticosteroids in patients with asthma and chronic obstructive pulmonary disease (COPD). Repurposing utilizes the advantages that the pulmonary route offers in terms of more targeted delivery to the site of action, the use of smaller doses, and a lower incidence of side-effects. Success has been more variable for other drugs and treatment indications. Pulmonary deliv...
Source: Advanced Drug Delivery Reviews - Category: Drugs & Pharmacology Authors: Tags: Adv Drug Deliv Rev Source Type: research
Nontuberculous mycobacteria (NTM) are an important emerging threat to cystic fibrosis (CF) patients. In North America, where the incidence of NTM in CF patients is ≥11.8%, Mycobacterium abscessus complex (MABSC), a multidrug-resistant NTM, accounts for ~35% of these [1], is notoriously recognised as difficult to eradicate, and seriously affects morbidity and mortality in CF [2] as well as lung transplantation outcomes [3, 4]. The mechanisms for the increased incidence of MABSC infection in CF patients are not known. The immune response in CF patients is directed to the Th2 response, which is associated with poorer clini...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Research letters Source Type: research
In this study we investigated regulatory t cells after combined lung and liver transplantation, or after isolated lung transplantation, in cystic fibrosis patients and correlated the findings with long term outcomes
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Patients with cystic fibrosis (CF) may have pulmonary infection with multi-drug resistant organisms (MDRO) potentially impacting post-transplant mortality. Our objective was to study 1-year mortality in CF patients with MDRO compared to those without MDRO lung transplant recipients (LTR) querying the largest international registry.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Early detection of Mycobacterium abscessus complex (MABSC) is crucial for patients with chronic lung disease to enhance the opportunity for potential eradication. Colonisation with MABSC is an absolute contra indication to lung transplantation in many transplant centres. Isolation of MABSC and other non-tuberculous mycobacteria (NTM) by traditional AFB culture is problematic, particularly from patients with cystic fibrosis (CF). Cultures are frequently overgrown by other bacteria or fungi and sputum decontamination procedures can reduce the viability of NTM.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Lobar lung transplantation is known as an alternative for higher Donor/Receiver mismatch in cystic fibrosis or idiopathic pulmonary fibrosis patients. Using lobar lung transplantation for Pulmonary Hypertension remains questionable because of the higher risk of primary graft dysfunction. We thought to determine wether lobar lung transplantation from brain-dead donors is an option for Pulmonary Hypertension.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
This study aims to characterize this acute airway inflammation in association with ACR status.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
We report our experience of LTx for CF patients infected with BCC.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
More News: Cystic Fibrosis | Health | Lung Transplant | Transplant Surgery | Transplants