IgG4-related cranio-spinal hypertrophic pachymeningitis involving the internal auditory canal.

IgG4-related cranio-spinal hypertrophic pachymeningitis involving the internal auditory canal. J Biol Regul Homeost Agents. 2016 Jul-Sep;30(3):915-919 Authors: Yangue Y, Gambaracci G, Floridi P, Fiacca A, Guerriero A, Giansanti M, Scialpi M Abstract Immunoglobulin G4 (IgG4)-related hypertrophic pachymeningitis, which is a focally or diffusely thickened dura mater and lymphoplasmacytic infiltration with increased IgG4 bearing plasma cells, is a rare disease, and cases involving the whole cervical spine are even rarer. Here, we describe a case of probable IgG4-related hypertrophic pachymeningitis involving the whole cervical spine and the auditory canals in an 18-year-old male. The patient, who had a history of paresthesia and had previously experienced weakness, presented with generalized tonic seizures. A decompressive laminectomy on cervical vertebrae was performed as a matter of urgency, removing intradural fibrous material. The patient responded well to treatment and was discharged walking independently, with no strength deficit to any of the 4 limbs, and with normal blood tests. PMID: 27655521 [PubMed - as supplied by publisher]
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research