Identifying  conditions for elimination and epidemic potential of methicillin-resistant Staphylococcus aureus in nursing homes

ConclusionsBased on our model, MRSA elimination from nursing homes, while theoretically possible, was unlikely to be achieved in practice. Decolonization therapy that can sustain higher clearance rates or lower MRSA-positive introductions over years may reduce strain-specific prevalence of MRSA in the facilities, and antibiotic stewardship may contribute to this effort. Large-scale MRSA outbreaks were unlikely in this setting.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research

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Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Basu Dev Pandey, Anthony Costello
Source: The Lancet - Category: General Medicine Source Type: research
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Source: The Lancet - Category: General Medicine Source Type: research
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Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
Conclusions: We present the most detailed genomic analysis of MRSA isolated in Sri Lanka to date. The analysis identified a PVL-positive ST5-MRSA-IVc that is prevalent among MRSA causing clinical infections in Sri Lanka. Furthermore, this clone was also found among isolates from the United Kingdom and Australia. Introduction Worldwide, Staphylococcus aureus is the primary causative agent of community-acquired skin and soft tissue infections (SSTI) and is an important cause of hospital-associated invasive infections including bacteremia, pneumonia and endocarditis (Bell et al., 2002; David and Daum, 2010). Panton-Va...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
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Source: Genome Research - Category: Genetics & Stem Cells Authors: Tags: RESOURCES Source Type: research
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