Identifying  conditions for elimination and epidemic potential of methicillin-resistant Staphylococcus aureus in nursing homes

ConclusionsBased on our model, MRSA elimination from nursing homes, while theoretically possible, was unlikely to be achieved in practice. Decolonization therapy that can sustain higher clearance rates or lower MRSA-positive introductions over years may reduce strain-specific prevalence of MRSA in the facilities, and antibiotic stewardship may contribute to this effort. Large-scale MRSA outbreaks were unlikely in this setting.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research

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If we keep allowing this virus to spread through unvaccinated populations, the next variant could be even more deadlyCoronavirus – latest updatesSee all our coronavirus coverageIt ’s almost two years since we first heard of Covid-19, and a year since the first Covid vaccines were rolled out. Yet this staggering progress is being squandered. We have drifted for months now, with richer countries, taking a very blinkered domestic focus, lulled into thinking that the worst of t he pandemic was behind us. This variant reminds us all that we remain closer to the start of the pandemic than the end.There is a lot we ne...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus Infectious diseases Vaccines and immunisation Health Epidemics Science Society World Health Organization Source Type: news
Their numbers could rise to over 60 cases, authorities said on Friday. #safrica #omicronoutbreak
Source: Reuters: Health - Category: Consumer Health News Source Type: news
In conclusion, boron-containing composite carbon quantum dots appear to be the most suitable delivery system for treating COVID-19 infections especially when they are delivered through the lung.
Source: Iranian Journal of Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research
The five patients had mild symptoms and were among 12 known coronavirus cases linked to a wedding in Wisconsin late last month.
Source: L.A. Times - Health - Category: Consumer Health News Authors: Source Type: news
The Wisconsin Department of Health Services (DHS) and the City of Milwaukee Health Department are investigating a COVID-19 outbreak from a wedding in Milwaukee County on November 27. There are currently 12 confirmed cases among California residents who attended the event. One of the individuals attended the wedding upon return from international travel. A California State lab used genomic sequencing to identify that 5 of the 12 people diagnosed with COVID-19, were infected with the Omicron...(see release)
Source: Wisconsin DHFS Press Releases - Category: Hospital Management Authors: Source Type: news
nneth A. Stapleford Epidemic RNA viruses seem to arise year after year leading to countless infections and devastating disease. SARS-CoV-2 is the most recent of these viruses, but there will undoubtedly be more to come. While effective SARS-CoV-2 vaccines are being deployed, one approach that is still missing is effective antivirals that can be used at the onset of infections and therefore prevent pandemics. Here, we screened FDA-approved compounds against SARS-CoV-2. We found that atovaquone, a pyrimidine biosynthesis inhibitor, is able to reduce SARS-CoV-2 infection in human lung cells. In addition, we found that ber...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
CONCLUSIONS: When prescribing antibiotics, it is essential to know the local trends in antibiotic resistance. Ozenoxacin cream 1% is highly effective against S. pyogenes and S. aureus, including methycyllin-susceptible and resistant strains (MRSA), and may be a suitable option for localized impetigo.J Drugs Dermatol. 2021;20(2):134-142. doi:10.36849/JDD.2021.5475 THIS ARTICLE HAD BEEN MADE AVAILABLE FREE OF CHARGE. PLEASE SCROLL DOWN TO ACCESS THE FULL TEXT OF THIS ARTICLE WITHOUT LOGGING IN. NO PURCHASE NECESSARY. PLEASE CONTACT THE PUBLISHER WITH ANY QUESTIONS. PMID: 33538559 [PubMed - as supplied by publisher]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Conclusions: We present the most detailed genomic analysis of MRSA isolated in Sri Lanka to date. The analysis identified a PVL-positive ST5-MRSA-IVc that is prevalent among MRSA causing clinical infections in Sri Lanka. Furthermore, this clone was also found among isolates from the United Kingdom and Australia. Introduction Worldwide, Staphylococcus aureus is the primary causative agent of community-acquired skin and soft tissue infections (SSTI) and is an important cause of hospital-associated invasive infections including bacteremia, pneumonia and endocarditis (Bell et al., 2002; David and Daum, 2010). Panton-Va...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
The correct interpretation of microbial sequencing data applied to surveillance and outbreak investigation depends on accessible genomic databases to provide vital genetic context. Our aim was to construct and describe a United Kingdom MRSA database containing over 1000 methicillin-resistant Staphylococcus aureus (MRSA) genomes drawn from England, Northern Ireland, Wales, Scotland, and the Republic of Ireland over a decade. We sequenced 1013 MRSA submitted to the British Society for Antimicrobial Chemotherapy by 46 laboratories between 2001 and 2010. Each isolate was assigned to a regional healthcare referral network in En...
Source: Genome Research - Category: Genetics & Stem Cells Authors: Tags: RESOURCES Source Type: research
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