Progressive lesions of Central Nervous System in microcephalic fetuses with suspected congenital Zika virus syndrome

ConclusionsThe majority of cases of congenital Zika virus syndrome will have additional ultrasonografic findings other than pure microcephaly. Progressive slowed growth rate of fetal head seems to better define Zika virus CNS anomalies, and this seems to be evident only in late second trimester, even when maternal infection occurs in the first trimester. Other ultrasound findings such as ventriculomegaly, brain calcifications and posterior fossa destruction lesions are also common in this congenital syndrome. Posterior fossa destruction lesions and arthrogryposis are an uncommon findings in other congenital infections. This may suggest a novel severe congenital syndrome, associated to fetal ZIKV.

Source: Ultrasound in Obstetrics and Gynecology - September 18, 2016 Category: Radiology Authors: Manoel Sarno, Marcelo Aquino, Kleber Pimentel, Renata Cabral, Gisela Costa, Fernanda Bastos, Carlos Brites Tags: Original Paper Source Type: research