Outcome of Adolescents and Young Adults Compared to Pediatric Patients with Acute Myeloid and Promyelocytic Leukemia

Conclusion Our analysis shows AYAs with AML have worse EMR and OS compared to pAML. AYAs with APL and pAPL patients have similar outcomes. To our knowledge, this is the first study reporting outcomes of AYAs and pediatric APL patients using large population based registry with comparison to same age AML patients. Teaser Studies on outcome of adolescents and young adults (AYAs) with acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL) are limited. We compared outcomes of AYAs (19-30 years) and pediatric (0-18 years) AML and APL patients using SEER-18 registry. AYAs with AML have worse early mortality and overall survival compared to pediatric AML, while AYAs and pediatric APL patients have similar outcomes.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research