Brain cancer deadliest cancer for children, study shows

Brain cancer has surpassed leukemia as the deadliest cancer for children and teens in the United States, new federal data show.
Source: WDSU.com - Health - Category: Consumer Health News Source Type: news

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This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, Rab1A knockdown repressed proliferation and promoted apoptosis in GC cells by inhibition of the mTOR/p70S6K pathway. PMID: 32240637 [PubMed - as supplied by publisher]
Source: Archives of Biochemistry and Biophysics - Category: Biochemistry Authors: Tags: Arch Biochem Biophys Source Type: research
Abstract Metastasis in the pineal region is a rare condition. To best of our knowledge, there is no case report of isolated pineal metastasis secondary to acute lymphocytic leukemia (ALL). The aim of this study is to show the pineal gland involvement of ALL in a case for the first time in the literature. A 25-year-old male patient diagnosed with ALL 2 years ago presented with headache and visual impairment. Brain magnetic resonance imaging (MRI) revealed a well-defined solid lesion which was revealed intensive enhancement after contrast. On diffusion-weighted images, the lesion showed significant diffusion r...
Source: Cancer Biology and Therapy - Category: Cancer & Oncology Authors: Tags: Cancer Biol Ther Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, we intravenously administrated the young mitochondria into aged mice to evaluate whether energy production increase in aged tissues or age-related behaviors improved after the mitochondrial transplantation. The results showed that heterozygous mitochondrial DNA of both aged and young mouse coexisted in tissues of aged mice after mitochondrial administration, and meanwhile, ATP content in tissues increased while reactive oxygen species (ROS) level reduced. Besides, the mitotherapy significantly improved cognitive and motor performance of aged mice. Our study, at the first report in aged animals, not only prov...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions: In anthracycline-treated cancer patients, the increase in plasma levels of NT-proBNP and of hs-cTnT can predict the development of anthracycline-induced cardiomyopathy. Early identification of at-risk patients will potentially allow for targeted dose reductions and will diminish the number of patients developing cardiac pathology.
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Original Investigations Source Type: research
CONCLUSION: GDM is associated with a greater risk of cancer in women, including breast, thyroid, stomach and liver cancers. However, further investigation is nonetheless warranted. PMID: 32097717 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - Category: Endocrinology Authors: Tags: Diabetes Metab Source Type: research
About 2000 children and adolescents under the age of 18 are diagnosed with cancer each year in Germany. Because of current medical treatment methods, a high survival rate can be reached for many types of the d...
Source: BMC Pediatrics - Category: Pediatrics Authors: Tags: Study protocol Source Type: research
Cancer is the third leading cause of death worldwide and the second common cause of death in developing countries [1,2]. To meet this alarming situation, many anticancer drugs have been developed. Cyclophosphamide (CP) is a drug that belongs to the class of alkylating agents [3]. CP is a potent anticancer and immunosuppressant drug that shows promising therapeutic utility against hepatocarcinoma, lung carcinoma, brain tumor, acute myeloid leukemia, and autoimmune diseases [4]. CP is a pro-drug with its two active metabolites, phosphoramide mustard (PM) and acrolein.
Source: Experimental Hematology - Category: Hematology Authors: Tags: Regular submission Source Type: research
Cancer is the third leading cause of death worldwide and the second common cause of death in the developing countries [1,2]. To meet this alarming situation, many anticancer drugs have been developed and CP is one the drug that belongs to the class of alkylating agents [3]3. CP is a potent anticancer and immunosuppressant drug that shows promising therapeutic utility against hepatocarcinoma, lung carcinoma, brain tumor, acute myeloid leukemia and against autoimmune diseases [4]. CP is a prodrug with its two active metabolites, phosphoramide mustard (PM) and acrolein.
Source: Experimental Hematology - Category: Hematology Authors: Source Type: research
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