Characteristics and survival outcome analysis of extramedullary involvement in adult patients with t(8;21) acute myeloid leukemia
Extramedullary involvement in acute myeloid leukemia with t(8;21) is not a rare manifestation. Extramedullary involvement has been regarded as a poor prognostic factor although t(8;21) is a favorable-risk karyotype. We analyzed 154 patients and identified extramedullary involvement was associated with young age, leukocytosis, and c-kit mutation. Outcomes were similar after transplantation-based treatment strategy regardless of extramedullary involvement.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Sung-Soo Park, Jae-Ho Yoon, Hee-Je Kim, Young-Woo Jeon, Sung-Eun Lee, Byung-Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Chang-Ki Min, Seok-Goo Cho, Dong-Wook Kim, Jong-Wook Lee, Woo-Sung Min Tags: Original Study Source Type: research
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