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Antimalarial Activity of the Fractions from Ethanol Extract of Strychnos ligustrina Blume. Wood

Conclusion: Extractive substances of S. ligustrina wood were very potential sources for natural antimalarial drugs. Fractionation ethanol extract of S. ligustrina wood produced fraction F3 and F4 were very active in inhibiting the growth of P. falciparum. These results strongly suggested that F3 and F4 of S. ligustrina wood were potential sources for antimalarial agents. For future development, it is neccesary for further studies to obtain the antimalarial active compounds from fraction F3 and F4 as an alternative new malaria drugs as well as material alternative drug combinations with artemisinin to get the optimal treatment of malarial.
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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Authors: Colomba C, Trizzino M, Gioè C, Coelho F, Lopo I, Pinheiro P, Sousa J, Cascio A PMID: 29460870 [PubMed - in process]
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research
Authors: Nanda N, Singh SP, Prajapati BK, Ranjan K, Kar NP, Sharma SK, Valecha N Abstract Background &objectives: Entomological investigations were carried out in highly malarious villages under Ujina PHC of District Nuh (Haryana state) which is an epidemic prone area in northwestern region of India. The study was aimed to have an in-depth understanding of the entomological parameters influencing malaria transmission in the study area. Methods: The seasonal prevalence and biological attributes of vector mosquitoes were investigated during 2015 and 2016. Indoor resting vector mosquitoes were collected from h...
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research
This study was carried out to compare the blood-feeding behaviour of An. sinensis in malaria-endemic areas of Shandong province China. Methods: Adult Anopheles mosquitoes were collected from three malaria-endemic areas (Jimo, Yinan and Shanxian), during the peak months of mosquito population (August and September) from 2014 to 2015. Indoor-resting mosquitoes and outdoor-resting blood-fed females were sampled in the morning hours (0600 to 0900 hrs) from 10 randomly selected houses using pyrethrum spray catch method, and sweeping with an insect net. ELISA was used for the identification of blood meal. The blood meal of e...
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research
This study provides laboratory confirmation that FTA cards can be used to capture and stabilize expectorated DENV-2 particles and P. falciparum sporozoites from infectious, sugar-feeding mosquitoes in very low numbers. Thus, the FTA card-based mosquito saliva capture method offers promise to overcome current limitations and revolutionize traditional mosquito-based pathogen surveillance programmes. Field testing and further method development are required to optimize this strategy. PMID: 29460859 [PubMed - in process]
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research
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Source: Journal of Parasitic Diseases - Category: Parasitology Source Type: research
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Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
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Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
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Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
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Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
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