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Specific Cytotoxicity of a Novel Arbutin Derivative from Myrothamnus flabellifolius Against Human Leukemia Cells

Conclusion: The data from this study has led in establishing a novel arbutin derivative to be specifically cytotoxic to acute myeloid leukemia cells. This compound can be chemically modified and developed as a potential anti-leukemia drug.
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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The Daily Mail's resident GP answers your queries on everything and anything. This week,he deals with the effects of airport scanners, allergies chronic pain.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
AbstractBayesian Additive Regression Trees (BART) is a statistical sum of trees model. It can be considered a Bayesian version of machine learning tree ensemble methods where the individual trees are the base learners. However, for datasets where the number of variablesp is large the algorithm can become inefficient and computationally expensive. Another method which is popular for high-dimensional data is random forests, a machine learning algorithm which grows trees using a greedy search for the best split points. However, its default implementation does not produce probabilistic estimates or predictions. We propose an a...
Source: European Journal of Applied Physiology - Category: Physiology Source Type: research
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Source: Molecular Carcinogenesis - Category: Molecular Biology Authors: Tags: RESEARCH ARTICLE Source Type: research
COUGH syrups and other treatments may help to relieve the condition. But, you should always see a GP if you have a severe, dry hacking cough.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Old age is a risk factor for cancer development in humans and animals, and studies have shown that tumors in animals are acceptable models for studying human cancers, considering the similarities between their factors. This work was conducted in a 53-year-old captive female common hippo (Hippopotamus amphibious) with a left leg tumor and metastatic mass. Histopathological and immunohistochemical analyses were carried out with a final diagnosis of a high grade pleomorphic sarcoma. A proteomic study using mass spectrometry was added in order to identify further aspects of the primary tumor and metastasis which could improve ...
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research
New J. Chem., 2018, Accepted Manuscript DOI: 10.1039/C7NJ04633B, PaperLina Cellante, Roberta Costa, Ilaria Monaco, GIOVANNA CENACCHI, Erica Locatelli Fisher esterification reaction has been exploited for linking a peptide (Chlorotoxin) onto the surface of nanocellulose by using a Bronsted acid ionic liquid both as solvent and catalyst. Indeed, cellulose... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Dalton Trans., 2018, Advance Article DOI: 10.1039/C7DT04093H, PaperArif Gulzar, Jiating Xu, Liangge Xu, Piaoping Yang, Fei He, Dan Yang, Guanghui An, Mohd Bismillah Ansari The disulfide bond (-S-S-) is an enormously valuable functional group in a variety of chemical and biological agents that display effective reactivity or biological activities (e.g., antitumor activities). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
CANCER symptoms vary depending on which part of the body is affected by the tumour. Back pain and weight loss could be a sign of the bladder disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Scientists are racing to understand why immunotherapy drugs have worked for a few cancer patients when the medicines should have had no effect.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Ovarian Cancer Immune System Tumors Immunotherapy Drugs (Pharmaceuticals) Dana-Farber Cancer Institute Johns Hopkins Medical Center Memorial Sloan-Kettering Cancer Center Sharma, Padmanee (1970- ) Pardoll, Drew Source Type: news
Conditions:   Cancer of Endometrium Stage I;   Cancer of Endometrium Stage II Interventions:   Procedure: Standard surgical procedure for endometrial cancer;   Procedure: systematic lymphadenectomy (LNE) Sponsors:   Philipps University Marburg Medical Center;   German Cancer Aid Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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