DNA Methylation in Oral Tongue Tumors

This study reveals a functional minimal methylation profile in oral tongue tumors with associated risk habits, clinical, and epidemiologic outcomes. In addition, NR4A3 downregulation and correlation with patient survival suggests a potential target for therapeutic intervention in oral tongue tumors. Data from the current study are deposited in the NCBI Geo database (accession number GSE75540). Mol Cancer Res; 14(9); 805–19. ©2016 AACR.

Source: Molecular Cancer Research - September 12, 2016 Category: Cancer & Oncology Authors: Krishnan, N. M., Dhas, K., Nair, J., Palve, V., Bagwan, J., Siddappa, G., Suresh, A., Kekatpure, V. D., Kuriakose, M. A., Panda, B. Tags: Genomics Source Type: research