Recurrent pneumonia and vaccine associated paralytic polio in a child with X linked agammaglobulinemia
This report suggests the importance of evaluating patients with vaccine associated paralytic polio (VAPP) for immunodeficiency diseases. We describe a child with VAPP and recurrent pneumonias who had underlying X linked agammaglobulinemia.
Publication date: Available online 10 December 2019Source: Parasitology InternationalAuthor(s): L. Buffoni, M.M. Piva, P. Baska, K. Januszkiewicz, L.J. Norbury, K.C. Prior, D. Dezen, A.S. Silva, H. Wedrychowiczhz, R.E. MendesAbstractThe aim of this study was to assess the immune response and the protective efficacy elicited by the vaccination with the recombinant Fasciola hepatica myosin regulatory light chain (FhrMRLC) in Adjuplex® adjuvant against the infection with F. hepatica in rats. Four groups of 15 animals each were used for the study, one group was immunized with the recombinant F. hepatica MRLC in Adjuplex&re...
In this study, we generated two recombinant RABVs, rERAG333E/NiVG and rERAG333E/NiVF, expressing the NiV Malaysian strain attachment glycoprotein (NiV-G) or fusion glycoprotein (NiV-F) gene based on the rERAG333E vector platform. Both rERAG333E/NiVG and rERAG333E/NiVF displayed growth properties similar to those of rERAG333E and caused marked syncytia formation after co-infection in BSR cell culture. Adult and suckling mice intracerebrally inoculated with the recombinant RABVs showed NiV-G and NiV-F expression did not increase the virulence of rERAG333E. Oral vaccination with rERAG333E/NiVG either singularly or combined wi...
Publication date: Available online 11 December 2019Source: Fish &Shellfish ImmunologyAuthor(s): Saekil Yun, Seung-Jun Lee, Sib Sankar Giri, Hyoun Joong Kim, Sang Geun Kim, Sang Wha Kim, Se Jin Han, Jun Kwon, Woo Taek Oh, Se Chang ParkAbstractThe aim of this study was to develop and evaluate a novel route of administration for vaccinating fish against Aeromonas hydrophila infection using a dissolving microneedles (MNs) patch. The A. hydrophila JUNAH strain was inactivated with formalin and used as a vaccine antigen. It was mixed with dissolvable carboxymethyl cellulose (CMC) as the matrix material to produce the MNs pat...
Authors: Abstract "My biggest motivation is the discovery of new therapeutics to save lives. The most significant scientific advance of the last 100 years has been the discovery of polio vaccine …" Find out more about Yanli Zhao in his Author Profile. PMID: 31816177 [PubMed - in process]
The objective of this paper is to provide useful definitions for understanding the methods used and their possibilities, and report current and future developments for thoracic imaging. Prospective validation of AI tools will be required before reaching routine clinical implementation.
Date: Tuesday, 12 17, 2019; Speaker: Dr. Erin Beck, NINDS; Dr. Kenneth Tyler, University of Colorado School of Medicine; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit
Review recent changes in ACIP's recommendations for pneumococcal conjugate vaccine use in older adults.Morbidity &Mortality Weekly Report
[VOA] Members of measles vaccination teams in southern Cameroon have been attacked and beaten by locals who say the serums triggered side effects that sent 12 children to local hospitals.
Extending human papillomavirus (HPV) vaccination to middle-aged adults would be costly and likely yield only small added health benefits, according to a health economic model.Reuters Health Information
Samoa said on Saturday nearly 90% of eligible people had been vaccinated against measles as it lifted a two-day curfew imposed amid an outbreak that has killed 65 in recent weeks.Reuters Health Information