Utility of 18 F ‐FDG PET/CT scan to diagnose the etiology of fever of unknown origin in patients on dialysis

In this study, we used 18 F‐FDG PET/CT scan whole body survey for detection of hidden infection, in patients on dialysis, labelled as FUO. Methods In this retrospective study, 20 patients of end stage renal disease on dialysis were investigated for the cause of FUO using 18F‐FDG PET/CT scan. All these patients satisfied the definition of FUO as defined by Petersdorf and Beeson. Any focal abnormal site of increased FDG concentration detected by PET/CT, either a solitary or multiple lesions was documented and at least one of the detected abnormal sites of radio tracer concentration was further examined for histopathology. Findings All patients were on renal replacement therapy. Of these, 18 were on hemodialysis and two were on peritoneal dialysis. 18F‐FDG PET/CT scan showed metabolically active lesions in 15 patients and metabolically quiescent in five patients. After 18F‐FDG PET/CT scan all, but one patient had a change in treatment for fever. Anti‐tuberculous treatment was given in 15 patients, antibiotics in four patients and anti‐malaria treatment in one patient. Discussion The present study is first study of 18F‐FDG PET/CT scan in patients of end stage renal disease on dialysis with FUO. The study showed that the 18 F FDG PET/CT scan may present an opportunity to attain the diagnosis in end stage renal disease patients on dialysis with FUO.
Source: Hemodialysis International - Category: Hematology Authors: Tags: Original Article Source Type: research

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Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Medical Practice Patients Climate Change equal opportunity Phuoc Le Sam Aptekar Source Type: blogs
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Source: TrAC Trends in Analytical Chemistry - Category: Chemistry Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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Source: BMC Medicine - Category: Internal Medicine Authors: Tags: Research article Source Type: research
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Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
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Source: International Journal of Dermatology - Category: Dermatology Authors: Tags: Review Source Type: research
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Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
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Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
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Source: Trials - Category: Research Source Type: clinical trials
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